重症急性胰腺炎36例治疗体会

EXPERIENCE IN TREATMENT OF 36 CASES SEVERE ACUTE PANCREATITIS

目的:探讨重症急性胰腺炎的临床特点和治疗方法。方法:回顾性分析36例重症急性胰腺炎患者的治疗资料。结果:综合性保守治疗24例,3例死亡(12.5%,3/24);手术治疗12例,1例死亡(8.3%,1/12)。死亡原因包括多脏器功能衰竭、急性呼吸窘迫综合征、感染性休克、应激性溃疡上消化道大出血等。结论:重症急性胰腺炎应据病情强调"个体化"治疗原则,把握好手术适应证和手术时机是提高重症急性胰腺炎治愈率和降低病死率的关键。

Objective： To investigate the clinical features and treatments of severe acute pancreatitis.Methods：The clinical data of 36 severe acute pancreatitis patients were retrospectively analyzed.Results：24 patients received comprehensive conservative treatments, among which 3 patients died, and the death rate was 12.5% （3/24）; 12 patients received surgical therapy, and 1 patient died, the death rate was 8.3% （1/12）. The causes of death included multiple organ failure, acute respiratory distress syndrome, infectious shock and stress ulcer upper gastrointestinal bleeding. Conclusions：Severe acute pancreatitis should adopt personalized treatment planning. It is the key to improve cure rate and reduce mortality that grasp surgical indications and surgical timing.