1Kuegler PB, Zimmer B, Waldmann T, et al. Markers of murine embryonic and neural stem cells, neurons and astrocytes., refer- ence points for developmental neurotoxicity testing [J]. ALTEX, 2010, 27(1): 17-42.
2Crofton KM, Mundy WR, Lein PJ,et al. Developmental neuro- toxicity testing- recommendations for developing alternative meth- ods for the screening and prioritization of chemicals [J]. ALTEX, 2011, 28(1): 9-15.
3Lieberman R, Levine ES, Kranzler HR, etal. Pilot study of iPS- derived neural cells to examine biologic effects of alcohol on hu- man neurons in vitro [J]. Alcoholism, clinical and experimental research, 2012, 36(10) : 1678-1687.
4Meltzer H, Hatton JD, Sang UH. Cell type-specific development of rodent central nervous system progenitor cells in culture [J]. J Neuro, 1998, 88(1): 93-98.
5Wiles MV, Johansson BM. Embryonic stem cell development in a chemically defined medium [J]. Exp Cell Res, 1999, 247 ( 1 ) : 241-248.
6Lee SH, Lumelsky N, Studer L, et al. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells [J]. Nat Biotechnol, 2000, 18(6): 675-679.
7Lendahl U, Zimmerman LB, cKay RDG. CNS stem cells express a new class of intermediate filament protein[J]. Cell, 1990, 60 (4) : 585-595.
8Pacherik KJ, Eslner M, Bryja V,et al. Neural differentiation of mouse embryonic stem cells grown in monolayer [J]. Reprod Nu- tr Dev, 2002, 42(4): 317-326.
9Radio NM, Breier JM, Shafer TJ,et al. Assessment of chemical effects on neufite outgrowth in PC12 cells using high content screening [J]. Toxicol SCi, 2008,105 (1) : 106-118.
10Newcohib EW. bcl -2 protein expression in astrocytoma in rela- tion to patient survival and P57 gene status [J] . Acta Newro- pathologica, 1997, 94(4) :769-775.