加味温胆汤联合认知-行为疗法治疗痰热内扰型慢性失眠随机平行对照研究

Flavored Wendan Tang combined Cognitive-behavioral Therapy for Phlegm Heat in One Type of Random Parallel Controlled Study of Chronic Insomnia

[目的]观察加味温胆汤联合认知-行为疗法治疗痰热内扰型慢性失眠疗效。[方法]使用随机平行对照方法,将88例住院患者按掷骰子法随机分为两组。对照组44例认知-行为疗法,从心理改变睡眠态度及信念,放松疗法、刺激控制疗法、认知疗法、限制睡眠疗法等。1次/d,50min/次。治疗组44例温胆汤(川穹、甘草、石菖蒲各6g,法半夏、陈皮各9g,竹茹、胆南星、百合、远志、枳实、知母各12g,茯苓、夜交藤、炒枣仁各15g,珍珠母30g);1剂/d,水煎200mL,早晚口服。认知-行为疗法治疗同对照组。连续治疗56d为1疗程。观测临床症状、相关指标、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈7例,显效16例,有效17例,无效4例,总有效率90.91%。对照组痊愈6例,显效10例,有效15例,无效13例,总有效率70.45%。治疗组疗效优于对照组(P<0.05)。[结论]加味温胆汤联合认知-行为疗法治疗痰热内扰型慢性失眠效果显著,值得推广。

[Objective]To observe the flavored wendan tang combined cognitive-behavioral therapy for phlegm heat in one type of chronic insomnia curative effect. [Methods]Using random parallel control method,88 cases of hospitalized patients were randomly divided into two groups according to roll the dice method. The control group of 44 cases of cognitive-behavioral therapy,from the psychological changes of patients with sleep attitudes and beliefs,relaxation therapy,stimulus control therapy,cognitive therapy,sleep restriction therapy,etc. 1/ d,50 min/time. Treatment group（44 cases of wendan tang（Chuanqiong,Gancao,Shicangpu 6g,Fabanxia, Chenpi each 9g,Zhuru,Dannanxing,Baihe,Yuanzhi,Zhishi,Zhimu 12 g,Fuling,Yejiaoteng,Chaozaoren each 15g,Zhenzhumu 30g）1/d,boiling water 200 mL,oral sooner or later;Cognitive-behavioral therapy to treat with the control group. Continuous treatment of 56 d of 1 course of treatment. Observation of clinical symptoms,the relevant indicators,adverse reactions. As a course treatment,judge curative effect. [Results]In treatment group recovered in 7 cases,16 cases had marked effect,17 cases effective,4 had no effect,the total effective rate was 90.91%. Control group cure 6 cases,10 cases were markedly effective,effective 15 cases,13 cases of invalid,the total effective rate was 70.45%. The treatment group curative effect is better than that of control group（P〈0. 05）. [Conclusion] Flavored wendan tang combined cognitive-behavioral therapy for phlegm heat in one type of chronic insomnia effect is remarkable,is worth promoting.