血栓通联合依达拉奉治疗急性脑梗塞随机平行对照研究

Thrombosis Through Joint Treatment of Acute Cerebral Infarction with Dara in Random Parallel Controlled Study

[目的]观察血栓通联合依达拉奉治疗急性脑梗塞疗效。[方法]使用随机平行对照方法,将100例住院患者按掷骰子法随机分为两组。对照组50例调脂、脑保护及抗血小板药物,降低颅压;30mg依达拉奉+100mL5%生理盐水,2次/d,静滴。治疗组50例300mg血栓通注射液+250mL5%生理盐水,1次/d,静滴。连续治疗14d为1疗程。观测临床症状、NIHSS评分、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈18例,显效22例,有效9例,无效1例,恶化0例,总有效率98.00%。对照组痊愈6例,显效7例,有效24例,无效11例,恶化2例,总有效率74.00%。治疗组疗效优于对照组(P<0.05)。两组NIHSS评分均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]血栓通联合依达拉奉治疗急性脑梗塞效果显著,优于常规疗法,值得推广。

[Objective]To observe the adr mentioned thrombosis through joint curative effect for the treatment of acute cerebral infarction. [Methods]Using random parallel control method,100 cases of hospitalized patients were randomly divided into two groups according to roll the dice method. In the control group of 50 cases with conventional treatment,the conventional lipid,brain protection and antiplatelet agents,dehydration of cranial pressure so as to reduce the cranial pressure. Adr mentioned 30 mg＋5% of the 100 ml saline,2 times/d,static drops. Treatment group（50 cases of 300 mg of blood clots injection ＋ 250 ml of 5% saline,1/d,static drops. Continuous treatment of 14 d to 1 course of treatment. Observation of clinical symptoms,NIHSS score,adverse reactions. As a course treatment,judge curative effect. [Results] the treatment group（18 cases cured,22 cases were markedly effective,effective 9 cases,ineffective in 1 case,deteriorating 0 cases,total effective rate was 98.00%. Control group cure 6 cases,7 cases,24 cases effectively,invalid 11 cases and worse in 2 cases,total effective rate was 74.00%. The treatment group curative effect is better than that of control group（P〈0.05）. NIHSS score has improved the two groups（P〈0.05）, the treatment group improved better than that of control group（P〈0.05）.[Conclusion]Thrombosis through joint the adr in treatment of acute cerebral infarction effect is remarkable,is superior to conventional therapy, worthy of promotion of use.