穿透性角膜移植150例的临床研究

Clinical research on 150 cases of penetrating keratoplasty

目的:探讨穿透性角膜移植的主要病因、疗效及并发症。方法:回顾性分析2011-01/2013-06于我院行穿透性角膜移植术的患者150例150眼。结果:病因:角膜白斑99眼(66%),角膜变性18眼(12%),角膜溃疡15眼(10%),角膜内皮失代偿10眼(6.7%),圆锥角膜8眼(5.3%)。疗效:植片透明110例(73.3%)。视力≤0.05者42例(28%),0.05<视力≤0.3者60例(40%),视力>0.3者48例(32%)。并发症:主要并发症为免疫排斥反应28例(18.7%)。结论:穿透性角膜移植是治疗角膜疾病致盲的重要有效手段,但术后排斥反应仍是影响手术成功的主要因素。

AIM： To investigate the main reasons, effects and complications of penetrating keratoplasty. METHOTS： Retrospective analysis on 150 cases （ 150 eyes） of penetrating keratoplasty was done from Jan. 2011 to June 2013. RESULTS： Reasons： coneal lecuma 99 eyes （ 66%）;corneal degeneration 18 eyes （ 12%）; corneal ulcers 15 eyes （ 10%）; corneal endothelium decompensation 10 eyes （6. 7%）;keratoconus 8 eyes （5. 3%）. Effects：Grafts were transparent in 110 eyes （73. 3%）. There are 42 eyes （28%） less than or equal to 0. 05 in visual acuity,60 eyes （40%） better than 0. 05 and less than or equal to 0. 3 and 48 eyes （32%） better than 0. 3. Complication： The main complication was immune rejection （28 eyes, 18. 7%）. CONCLUSION：Penetrating keratoplasty is an important and effective means for keratitis disease.