川崎病96例临床分析

Clinical analysis of 96 cases with Kawasaki disease

目的比较不完全性川崎病与典型川崎病的临床特征,以期为川崎病的临床诊疗提供帮助。方法选择在我院住院部治疗过的96例川崎病患儿,分为不完全性川崎病组与典型川崎病组,比较两组的临床表现及治疗前的实验室指标。结果除肛周脱屑外,两组眼球结膜充血、口唇充血皲裂、皮疹、手足硬肿、指端脱皮,淋巴结肿大、草莓舌、冠状动脉病变的发生例数比较差异均有统计学意义(P<0.05)。应用药物治疗前,除血红蛋白外,白细胞、血小板、血沉、C反应蛋白、白蛋白比较差异无统计学意义(P>0.05)。结论对于不完全性川崎病,在排除其他疾病引起的发热后,参考血红蛋白下降及肛周脱屑可初步诊断为川崎病,以避免错过患儿的最佳治疗时机。

Objective To compare clinical characteristics of incomplete Kawasaki and typical Kawasaki, in order to provide help for clinical diagnosis and treatment. Methods 96 children with Kawasaki disease were divided into incomplete Kawasaki group and typical Kawasaki group, the clinical manifestations and laboratory indexes were compared between the two groups before treatment. Results In addition to the perianal desquamation, bulbar conjunctiva hyperemia, congestion, rash, hand foot chapped lips swollen, swollen lymph nodes, strawberry tongue, that the number of toe desquamate, comparison of coronary artery lesions of two groups showed significant differences（P〈0.05）. Before application of drug treatment, except hemoglobin, there were no statistical significance differences of white blood cells, platelets, ESR, C reactive protein, albumin in two groups（P0.05）. Conclusion For the incomplete Kawasaki disease, fever in the exclusion of other diseases, can diagnose the disease by reference hemoglobin decreasing and perianal desquamation for Kawasaki optimal treatment opportunity.