脑利钠肽在呼吸系统疾病中临床应用的研究进展

Research advances of brain natriuretic peptide in common diseases of respiratory system

目前,已经公认脑利钠肽（BNP）在心室容积扩张和压力负荷增加时分泌增加,并发现BNP对于急诊科是一种区分急性呼吸困难原因十分有用的标志物,而且对充血性心力衰竭患者预后具有判断价值.然而,BNP在很多情况下都可以升高,其中包括常见的呼吸系统疾病.最新发表的一些关于BNP对呼吸系统疾病监测治疗效果、危险分层、判断预后等文献使BNP的临床应用范围得到扩大.本文就BNP在常见呼吸系统疾病中临床应用的最新进展进行综述.

It is well-recognized that brain natriuretic peptide （BNP）is raised in conditions with ventricular volume and pressure overload.BNP has been found to be an useful marker in identifying acute dyspneic patients presenting to the emergency department and also a potent prognostic marker for patients with congestive heart failure.However,elevated BNP level has been found in many circumstances involving common respiratory diseases.Potential clinical applications of BNP are expanded accompanied by emerging reports regarding monitoring the therapeutic responses,risk stratifications and providing prognostic values.In this article,we reviewed the research advances of BNP in common respiratory diseases.