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蒙特利尔认知评估量表在腔隙性脑梗死患者中的临床应用观察 被引量:5

Evaluation about Montreal cognitive assessment scale in patients with lacunar infarction
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摘要 目的评价蒙特利尔认知评估量表(MoCA)在腔隙性脑梗死患者之认知状况评估中的应用价值,探讨腔隙性脑梗死患者不同领域的认知损害与其影像学所见病灶部位的相关性。方法 159例腔隙性脑梗死患者,依其MoCA和MMSE所得分值分为3组:认知功能正常对照组(MMSE分值在划界线以上及MoCA≥26分);观察组(MMSE分值在划界线以上但MoCA<26分);认知功能障碍对照组(MMSE分值在划界线以下及MoCA<26分)。记录各组患者的人口学资料、头MRI所见腔隙性脑梗死病灶部位、MoCA和MMSE分值,分析头MRI所见不同病灶部位与MoCA各子项目分值之间的关系,应用SPSS 17.0程序软件包等进行统计学分析。结果 (1)腔隙性脑梗死患者认知功能异常筛出率MMSE为38.36%,MoCA为83.01%;MMSE分值异常者中无MoCA分值正常者,MMSE分值正常者(占研究总体的61.63%)中有占研究总体44.65%者MoCA分值异常。(2)患者头MRI所见腔隙性脑梗死病灶部位多发,以额叶、顶叶、基底节最多见,其次为丘脑、脑干及侧脑室周围白质。(3)不同的梗死病灶部位所相关的认知损害领域也不同(P<0.05):额叶病灶与执行功能、视空间能力、注意与计算力、语言、抽象力、记忆力等损害相关,顶叶病灶与执行功能、视空间能力损害相关,基底节病灶与执行功能、记忆力、计算与注意力等损害相关,丘脑病灶与执行功能、记忆力、计算力、语言表达力、抽象思维力、定向力等受损相关,小脑病灶与执行功能、注意力、计算力受损相关,脑干病灶与执行功能、语言、记忆力损害相关,侧脑室周围白质损害与执行功能、语言、计算力、记忆等功能下降相关。结论 MoCA量表是评价腔隙性脑梗死患者认知功能障碍灵敏而客观的量表;腔隙性脑梗死患者的认知功能障碍是多领域的,不同梗死灶部位损害的认知领域不同。 Objective To evaluate the application value of Montreal Cognitive Assessment (MoCA)in patients with lacunar infarction (LI),and to explore the relevance of cognitive impairment in different areas and imaging of lesion site in patients with LI.Methods 159 cases were divided into three groups according to the MoCA and MMSE score,the control group with normal cognitive function (MMSE score above the demarcation line and MoCA score ≥ 26 points),the observation group (MMSE score above the demarcation line and the MoCA < 26points),the cognitive dysfunction group(MMSE score below the demarcation line and MoCA < 26 points).The demographic data of all patients,the LI lesion site in head MRI and the MoCA and MMSE score were recorded,the relation between the LI lesion site in head MRI and the MoCA and MMSE score were analysed.The results were calculated with SPSS 17.0.Results (1) The isolation rate of MMSE and MoCA of abnormal cognitive function in patients with LI were 38.36% and 83.01%.The MoCA scores of patients with abnormal MMSE score were also abnormal.In patients with normal MMSE score (accounting for 61.63% of the sample),the MoCA scores were abnormal which accounting for 44.65 % of total study population.(2)The head MRI findings showed that the lesion site of patients with LI occured multiply in frontal lobe,parietal lobe,basal ganglia,the most common,then the thalamus,brain stem and periventricular white matter.(3)The different infarct lesion sites were related to the different field of cognitive impairment(P < 0.05).The damage of the frontal lobe lesions were related to the damage of executive function,visuospatial ability,attention and calculation power,language,abstract force and memory.The damage of parietal lobe lesions were related to the damage of executive function,visuospatial ability damage.The harm of basal ganglia lesions were related to the damage of executive function,memory,calculation and attention damage.The injure of hypothalamic lesions were related to the injure of execution functions,memory and calculation,language ability,abstract thinking ability and disorientation.The injure of cerebellar lesions were related to the injure of executive function,attention.calculation damaged.The damage of lesions associated with executive function,language,memory damage.The injure of periventricular white matter were related to executive function,language,computing power,memory and other functions.Conclusion The MoCA Scale was sensitive and objective to evaluate the patients with lacunar infarction cognitive dysfunction.The cognitive dysfunction of patients with Lacunar infarction were various and the cognition of different infarct site were different.
出处 《中华临床医师杂志(电子版)》 CAS 2013年第11期73-76,共4页 Chinese Journal of Clinicians(Electronic Edition)
关键词 脑梗死 蒙特利尔认知评估量表 影像学 Brain infarction Montreal cognitive assessment Imaging
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  • 1Erkinjuntti T.Subcortical vascular dementia[].Cerebrovascular Diseases.2002
  • 2Jokinen H,Kalska H,Ylikoski R,et al.MRI-defined subcortical ischemic vascular disease:baseline clinical and neuropsychological findings.The LADIS Study[].Cerebrovascular Diseases.2009
  • 3Pedersen PM,Jrgensen HS,Nakayama H,et al.Impaired orientation in acute stroke:frequency,determinants and time-course of recovery.The Copanhagen Storke Study[].Cerebrovascular Diseases.1998
  • 4Vermeer SE,Prins ND,den Heijer T,et al.Silent brain infarcts and the risk of dementia and cognitive decline[].New England Journal of Homeopathy.2003

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