DDAH/ADMA系统与2型糖尿病动脉粥样硬化风险因素的关系被引量：3

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摘要糖尿病与动脉粥样硬化关系密切,表现为糖尿病患者出现动脉粥样硬化的时间早、程度重和预后差,而出现动脉粥样硬化的患者多伴有不同程度的糖代谢异常.在动脉粥样硬化的发生发展中,血管内皮受损起关键作用.众所周知,一氧化氮（NO）是重要的内源性血管舒张因子之一,非对称二甲基精氨酸（ADMA）是一种内源性一氧化氮合成酶（NOS）抑制剂,可从多条途径造成血管内皮功能损伤,促进动脉粥样硬化的发生和发展.

作者杨晶晶石柔宋滇平

机构地区昆明医科大学第一附属医院糖尿病科

出处《中华临床医师杂志（电子版）》 CAS 2013年第7期168-169,共2页 Chinese Journal of Clinicians(Electronic Edition)

基金云南省教育厅科学研究基金(2012Y023)

关键词糖尿病动脉粥样硬化风险因素一氧化氮合成酶非对称二甲基精氨酸血管内皮功能损伤血管舒张因子 2型系统

分类号 R587.1 [医药卫生—内分泌] R543.5 [医药卫生—心血管疾病]

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