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索拉菲尼在肿瘤治疗中的研究进展 被引量:18

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摘要 1906年,Enrilich首先提出靶向治疗的概念,是指在肿瘤的分子生物学基础上,以肿瘤组织或细胞所具有的特异性结构分子作为靶点,利用某些能与这些靶分子特异性结合的抗体、配体等,将具有肿瘤杀伤作用的药物或物质选择性地送到靶部位,达到直接治疗或导向治疗目的的一类疗法。靶向治疗将治疗作用或药物效应限定在特定靶细胞、组织或器官内,从而提高疗效,减少不良反应。目前研究认为,靶向药物在恶性肿瘤治疗中,不仅治疗效果明显优于传统治疗,而且毒副作用也显著减少。
出处 《中华临床医师杂志(电子版)》 CAS 2013年第1期137-139,共3页 Chinese Journal of Clinicians(Electronic Edition)
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