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阿尔兹海默病轴突病变的研究进展 被引量:8

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摘要 阿尔茨海默病(Alzheimer disease,AD)是一种由于脑海马和皮层神经细胞死亡而造成的、发生于老年和老年前期以进行性认知障碍和记忆力损坏为主的中枢神经系统退行性疾病。AD的发生是典型的渐进过程,在发病早期,短期记忆能力下降,并伴随有空间识别能力的下降;随着时间推移,记忆损伤严重;最终,患者的认知能力下降,语言和空间方向感缺失并丧失自主能力。
作者 卢兴平
出处 《中华临床医师杂志(电子版)》 CAS 2013年第14期166-167,共2页 Chinese Journal of Clinicians(Electronic Edition)
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参考文献32

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同被引文献70

  • 1邹存珍,郭迎喜,韩玉生.针刺足三里、关元穴对AD大鼠海马区离子泵ATP酶及线粒体体密度的影响[J].针灸临床杂志,2007,23(11):46-47. 被引量:4
  • 2沈卫东,金磊,李鼎.针灸对拟痴呆大鼠记忆功能及皮层胆碱能系统的影响[J].中国中西医结合杂志,2001,21(S1):40-42. 被引量:4
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  • 5Eugenio Barone,Fabio Di Domenico,Rukhsana Sultana,Raffaella Coccia,Cesare Mancuso,Marzia Perluigi,D. Allan Butterfield.Heme oxygenase-1 posttranslational modifications in the brain of subjects with Alzheimer disease and mild cognitive impairment[J].Free Radical Biology and Medicine (-).2012(11-12)
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  • 7D. Allan Butterfield,Eugenio Barone,Fabio Di Domenico,Giovanna Cenini,Rukhsana Sultana,Michael P. Murphy,Cesare Mancuso,Elizabeth Head.Atorvastatin treatment in a dog preclinical model of Alzheimer’s disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain[J].The International Journal of Neuropsychopharmacology.2011(7)
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