期刊文献+

放射治疗在乳腺癌患者综合治疗中的作用 被引量:1

Effect of radiotherapy in treatment of comprehensive treatment of breast cancer
下载PDF
导出
摘要 目的 探讨放射治疗在乳腺癌患者综合治疗中的作用.方法 选择2010年12月~2011年12月在本院治疗的70例Ⅰ、Ⅱ期乳腺癌患者,随机分为观察组与对照组,每组各35例,对照组采用保乳手术+术后辅助化疗,观察组在对照组的基础上加用放射治疗,比较两组患者的治疗效果及不良反应发生情况.结果 观察组的生存率为97.14% (34/35)、远处转移率为2.85% (1/35),对照组生存率为97.14%(34/35)、远处转移率2.85% (1/35),组间差异无统计学意义(P>0.05);观察组的局部复发率为2.85% (1/35),对照组为11.42% (4/35),组间差异有统计学意义(P<0.05);观察组的放疗不良反应共13例,对照组16例,组间差异无统计学意义(P>0.05);观察组患者的术后生存质量与外观美容效果均明显优于对照组,组间差异有统计学意义(P<0.05).结论 放射治疗能降低乳腺癌患者的术后复发率,提高美容效果与患者的生存质量,值得推广应用. Objective To investigate the effects of radiotherapy in comprehensive treatment of breast cancer patients. Methods 70 cases of Ⅰ , Ⅱ stage breast cancer patients treated in our hospital during December 2010 to December 2011 were selected,they were randomly divided into observation group and control group,35 cases in each group,the control group treated with breast-conserving surgery plus adjuvant chemotherapy,the observation group treated with ra- diotherapy based on the control group,the therapeutic effects and adverse reactions were compared. Results The sur- vival rate in observation group was 97.14%(34/35),distant metastasis rate was 2.85% (1/35),those of the control group was 97.14% (34/35), and 2.85% (1/35),no significant difference between the groups (P〉0.05).Local recurrence rate of observation group was 2.85% (1/35),that of the control group was 11.42% (4/35),the difference was statistically signifi- cant (P〈0.05).Observation group had 13 cases of adverse reactions,the control group had 16 cases of adverse reactions, there was no significant difference between the groups (P〉0.05).Postoperative quality of life and appearance cosmetic results of the observation group were significantly better than those of the control group (P〈0.05). Conclusion Radiation therapy can reduce the recurrence rate of breast cancer patients and improve cosmetic results and quality of life of pa- tients,it is worthly of popularization and application.
出处 《中国当代医药》 2014年第15期19-20,23,共3页 China Modern Medicine
基金 浙江省医药卫生平台重点资助计划(2012KYA071)
关键词 放射治疗 乳腺癌 复发率 效果分析 Radiation therapy Breast cancer Relapse rate Effectiveness analysis
  • 相关文献

参考文献9

二级参考文献96

  • 1倪青,魏娜,易亮.乳腺癌新辅助化疗42例临床观察[J].贵州医药,2007,31(6):512-513. 被引量:1
  • 2张涛,张保宁,余子豪,李晔雄,徐兵河.保乳手术在乳腺癌治疗中的应用[J].中国癌症杂志,2004,14(6):555-557. 被引量:29
  • 3任洪波,王琦,李少林,黄碧有.术前化疗结合放疗治疗炎性乳腺癌疗效分析[J].中国肿瘤临床,2006,33(7):384-385. 被引量:7
  • 4蔡海峰,赵刚,潘惠承.新辅助化疗在隐匿性乳腺癌中的应用[J].中国综合临床,2006,22(6):538-539. 被引量:4
  • 5Clarke M, Collins R, Darby S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomized trials. Lancet, 2005,366= 2087-- 2106.
  • 6Holland R, Veling S H, Mravunac M, et al. Histologic multifocality of Tis, T1-2 breast carcinomas: implications for clinical trials of breast conserving surgery. Cancer, 1985,56:979--990.
  • 7Schnall M. MR imaging evaluation of cancer extent: is there clinical relevance? Magn Reson Imaging Clin N Am, 2006, 14:379--381.
  • 8VeronesiU, MarubiniE, MarianiL, etal. Radiotherapy after breast conserving surgery in small breast carcinoma: long-term results of a randomized trial. Ann Oncol, 2001, 12:997--1003.
  • 9AbdAllaH M, I-tayefM M, AbouBakr A, et al. Ipsilateral in-breast tumor relapse after breast conservation therapy: true recurrence versus new primary tumor. J Egypt Natl Canc Inst, 2006,18:183--190.
  • 10Vicini F A, Kestin I. I., Goldstein N S. Defining the clinical target volume for patients with early-stage breast cancer treated with lumpectomy and accelerated partial breast irradiation:a pathologic analysis. Int J Radiat Oncol Biol Phys, 2004,60 : 722-- 730.

共引文献80

同被引文献4

引证文献1

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部