宫颈环形电切术治疗Ⅱ、Ⅲ级宫颈上皮内瘤变的临床价值分析

The clinical value of loop electrosurgical excision procedure(LEEP) treatment Ⅱ,Ⅲ grade cervical intraepithelial neoplasia(CIN)

目的 探讨宫颈环形电切术（LEEP）治疗Ⅱ、Ⅲ级宫颈上皮内瘤变（CIN）的临床价值.方法 选择2008年8月～2013年11月本院接诊的经相关检查确诊为Ⅱ、Ⅲ级CIN的90例患者为研究对象,按照随机数表法均分为两组,分别采用LEEP和宫颈冷刀锥切术（CKC）进行治疗.术后记录分析两组患者的术中出血量、手术时间及术后愈合时间,并随访调查两组患者术后并发症的发生率.结果 LEEP组的术中出血量明显少于CKC组（P＜0.01）,手术时间明显短于CKC组（P＜0.01）,术后愈合时间明显短于CKC组（P＜0.01）.LEEP组患者的并发症发生率明显低于CKC组,两组差异有统计学意义（x2=4.9390,P=0.0263）.结论 LEEP治疗Ⅱ、Ⅲ级CIN可显著改善患者的手术情况,降低术后并发症的发生率,安全性高.

Objective To investigate the clinical value of loop electrosurgical excision procedure （LEEP） treatment the Ⅱ,Ⅲ grade cervical intraepithelial neoplasia （CIN）. Methods 90 cases of Ⅱ, Ⅲ grade CIN patients were selected as the research object in our hospital from August 2008 to November 2013.According to the random number table method, they were randomly divided into two groups.The LEEP and cervical cold knife conization （CKC） were used to treat them respectively.After surgery,the blood loss,operative time and postoperative healing time of the patients were recorded and analyzed,and follow-up survey incidence of postoperative complications were studied. Results The blood loss of the LEEP group was significantly less than that of the CKC group （P〈0.01）,the operative time was significantly shorter than that of the CKC group （P〈0.01）,the postoperative healing time was significantly lower than that of the CKC group （P〈 0.01）.The incidence of complications in LEEP group was significantly lower than that of the CKC group,the two groups was statistically significant （χ 2=4.9390,P=0.0263）. Conclusion LEEP treatment Ⅱ,Ⅲgrade CIN can significantly im- prove patients＇ conditions,reduce the incidence of postoperative complications,has a high safety.