头孢拉定加肝素钠封管预防患者中心静脉置管相关性感染的效果

Preventive effect of cefradine plus heparin sealing catheters on central venous catheter-related infections

目的探讨头孢拉定加肝素钠封管预防患者中心静脉置管相关性感染的效果。方法将112例中心静脉置管患者随机分为对照组57例和干预组55例,对照组患者中心静脉置管期间给予肝素钠封管,干预组患者给予头孢拉定加肝素钠封管。比较两组患者中心静脉置管期间导管相关性感染情况。结果对照组患者中心静脉置管期间导管相关性感染率为12.28%,干预组为0.00%,两组比较,差异具有统计学意义(P<0.01)。结论中心静脉置管患者采用头孢拉定加肝素钠溶液封管,可有效降低患者导管相关性感染。

Objective To explore the preventive effect of Cefradine plus heparin sealing catheters on central center venous （CVC）catheter-related infections.Methods One hundred and twelve patients with central venous catheter were randomly divided into control group（n=57）and intervention group（n=55）.In the control group,heparin sodium was used to seal the catheters and in the intervention group Cefradine plus heparin were used.The two groups were compared in terms of central venous catheter（CVC）-related infections.Results The CVC-related infection rates are 12.28%and 0%in the control and intervention groups respectively, with statistical difference between them（P〈0.01）.Conclusions Cefazodine and heparin used to seal the catheters in the treatment of patients with central venous catheter can effectively reduce incidence of catheter-related infections.