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GLP-1对2型糖尿病胰岛细胞及脂肪细胞的作用研究 被引量：3

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摘要 胰岛α、β细胞及脂肪细胞在2型糖尿病(T2DM)发病过程中扮演了重要的作用,参与了T2DM的发生、发展全过程。胰高血糖素样肽-1(GLP-1)是一种肠促胰岛素,由肠道末端内分泌L细胞分泌,可促进胰岛素的释放。目前研究证明,GLP-1具有较好的控制T2DM患者血糖的作用。本文从T2DM发病机制着手,探讨T2DM基本发病机制,阐述近年来国内外对GLP-1与T2DM之间关系的研究,旨在为开发用于治疗糖尿病及胰岛移植的新药提供了理论依据。
作者 刘芳 余江毅
机构地区 南京中医药大学
出处 《医学研究杂志》 2014年第5期10-12,共3页 Journal of Medical Research
基金 江苏省自然科学基金资助项目(SBK201122365)
关键词 GLP-1 T2DM 胰岛细胞 脂肪细胞
分类号 R587 [医药卫生—内分泌]
  • 相关文献

参考文献18

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共引文献5

同被引文献59

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引证文献3

二级引证文献20

医学研究杂志
2014年 第5期

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