低氘白酒对人体脑电图和心理功能的作用

Effects of Deuterium-depleted Liquor on Brain and Psychological Functions

目的研究连续8天摄入低剂量或高剂量酒精、普通白酒和低氘白酒对人体脑电图上的alpha波相对功率值、alpha衰减系数(AAC)、主观感觉和血液中5-羟色胺含量的影响,探讨低氘白酒对人体中枢神经功能的影响并分析其可能的机制。方法 11名平均年龄为23.7±1.3岁的健康成年男性参加本实验。实验期间受试者分别饮用低剂量酒精、高剂量酒精、低剂量白酒、高剂量白酒、低剂量低氘白酒和高剂量低氘白酒。30min后检测脑电图,并计算α衰减系数(alpha attenuation coefficient,AAC)和alpha相对功率值,用视觉模拟评分法(visual analogue scale,VAS)测试受试者的舒适感和工作效率,作为主观评价的指标,同时采血样用于5-羟色胺含量的分析。结果α衰减系数结果显示,饮用高剂量酒精后AAC升高,其他组未见明显改变。与对照组相比,α波的平均功率值在饮用高、低剂量的酒精和白酒后均有明显下降,而饮用低氘白酒后α波的平均功率值未见明显下降,且比酒精和白酒组高,表明饮用酒精和白酒能使α波活动减少,而低氘白酒无此不良反应。血浆5-羟色胺的分析结果表明,饮用低剂量低氘白酒时血浆内的5-羟色胺水平最高,说明低氘白酒能引起人大脑的舒适感升高。结论饮用酒精和普通白酒能使人体脑电图上的α平均功率值下降,人体的舒适感和工作效率降低,而低氘白酒能使人体的α波相对功率值、舒适感、工作效率和5-羟色胺的含量都维持在较高的水平上,即饮用低氘白酒时,人体中枢神经的功能可维持在较为平衡稳定的水平上,避免调控的失衡的发生。

Objective To study the effect of deuterium - depleted liquor on brain function and evaluate the regulation of central nervous system for deuterium - depleted liquor in comparison with alcohol and ordinary Chinese liquor. Methods Eleven heathy adult male with an average age of 23.7 ± 1.2 participated in this experiment. The study was divided into seven experimental groups, such as normal control group （CK） , low- dose alcohol group （A- L） , high- dose alcohol group （A -H）, low- dose ordinary Chinese liquor group （ L - L） , high dose ordinary Chinese liquor group（ L - H） , low - dose deuterium - depleted Chinese liquor group（ DDL - L） and high- dose deuterium depleted Chinese liquor group（DDL- H）. We recorded the electroencephalography（EEG） on Fz. Results EEG showed that when sabiects drinking high or low doses of alcohol and ordinary Chinese liquor, the value of AAC had no significant change compared with the control group. But the mean power of the alpha band decreased significantly. Comparison with other groups, when sub- jects drinking high or low doses of the deuterium - depleted Chinese liquor, mean power of the alpha band increased significantly. This phenomenon might be caused by deuterium - depleted Chinese liquor biological activating effect. Compared with the control value, comfort and work efficiency decreased when subjects drinking alcohol and liquor descendants. The blood 5 - hydroxytryptamine increased signifi- cantly when subjects drinking low - dose deuterium - depleted Chinese liquor. Conclusion This study demonstrated that compared with the alcohol and ordinary Chinese liquor, the deuterium -depleted Chinese liquor induced pleasure, increased the intensity of the alpha waves on human EEG.