体外受精-胚胎移植后异位妊娠相关因素分析

Analysis of Ectopic Pregnancy after in vitro Fertilization and Embryo Transfer

目的分析体外受精(IVF)或卵母细胞胞质内单精子注射(ICSI)后进行新鲜或冻融胚胎移植(ET)妇女异位妊娠的发生情况及其影响因素。方法对接受胚胎移植治疗后获得临床妊娠的1564个周期的病因、年龄、移植时机、不育形式等高危因素进行回顾性调查。采用SPSS 17.0软件进行统计学分析,计数资料采用t检验,计量资料采用χ2检验,相关性统计采用Logistic回归分析。结果冻融周期ET后异位妊娠发生率明显低于新鲜周期ET。年龄≤30岁的患者ET后发生异位妊娠率高于年龄>30岁者,继发不孕者较原发不孕者发生异位妊娠的比例更高。结论年龄、移植时机和不育形式是体外受精-胚胎移植后发生异位妊娠的重要相关因素。

Objective A total of To investigate the incidence of ectopic pregnancy and influential factors of ectopic pregnancy in women with in fresh and cryopreservation thawed embryo transplantation after in vitro fertilization （IVF） or intracytoplasmic sperm injection （ICSI）. Methods A total of 1546 pregnancy cycles were studied retrospectively about its high risk factors as etiology, age, timing of mi- gration, and form of infertility. SPSS17.0 software was used, measurement data using t tests testing method, count data usingx2 test, correlation statistics using Logistic regression analysis, and there was significantly difference when P 〈 0.05. Results The ectopic pregnancy rate in cryopreservation thawed embryo transplantation is significantly lower than fresh embryo transplantation. The ectopic pregnancy rate of women under the age of 30 is much higher than those over 30 years old. The ectopic pregnancy rate in secondary infertility is much higher than primary infertility. Conclusion Age, timing of migration and form of infertility may be important factors with ectopic pregnancy after IVF - ET.