肝硬化胃肌电活动紊乱类型及发生原因初探

The Preliminary Study on the Type of Gastric Myoelectrical Activity Disorders and Its Causes in Liver Cirrhosis

目的:探讨肝硬化胃电变化及相关因素。方法:46例肝硬化患者和20例健康志愿者(对照组)测量空腹体表胃电图,对比主频、正常慢波百分比、胃电节律紊乱百分比、胃动过缓百分比、胃动过速百分比、无节律百分比等,分析胃电参数与白蛋白、电解质、child-pugh分级、食管静脉曲张的相关性。结果:与对照组相比,肝硬化胃电紊乱(胃动过速及胃动过缓)发生率明显增加(P<0.05);肝硬化胃动过缓与Child-pugh分级、食管静脉曲张程度呈正相关,与白蛋白、钾、钙离子呈负相关,胃动过速与钾离子负相关。结论:肝硬化患者胃动过缓及胃动过速发生率高,这可能与患者白蛋白、钾、钙离子水平及食道静脉曲张程度有关。

Objective： To explore the type of gastric electrical disorders and its related factors in liver cirrhosis. Methods： Preprandial electrogastrography was carried out in 46 cases with liver cirrhosis and 20 healthy volunteers （controls）, the dominant frequency, the percentage of normal slow wave, the percentage of gastric electrical dysrhythmia, bradygastria percentage, tachygastria percentage, no rhythm percentage of the two groups were compared. The relationship of gastric electrical indexes with albumin, electrolytes, child-push grades and esophageal varices was analyzed. Results： Compared with the control group, the incidences of gastric electrical dysrhythmia in liver cirrhosis group were increased. Bradygastria was positively correlated with child-pugh grading and esophageal varices, nega- tively correlated with albumin, potassium, calcium. And tachygastria was negatively correlated with the potassium. Conclusions： The incidences of tachygastria and bradygastria are increased in patients with liver cirrhosis, which may relate to the levels of albumin, potassium, calcium and esophageal variee grading