老年人眼肿瘤504例临床病理分析

Clinical and pathological analysis of 504 cases of elderly ocular tumors

目的:分析老年人眼部原发肿瘤的构成、分布情况及发病特点。方法:对我院病理科2000-01/2012-12收集的504例老年人眼部原发肿瘤的发病年龄、发病部位和病理类型进行回顾性分析。结果:患者504例眼部原发肿瘤中良性肿瘤346例(68.7%),恶性肿瘤158例(31.3%)。其中良性肿瘤中以乳头状瘤最多见占83例(16.5%),其次为各种囊肿和炎性病变分别为69例(13.7%)和64例(12.7%)。恶性肿瘤中以眼睑上皮来源的肿瘤基底细胞癌最多见,共72例(14.3%),其次为皮肤附件来源的恶性肿瘤39例(7.7%)。从发病部位来看眼睑肿物最多282例(56.0%),其次为眼角结膜肿物157例(31.2%)。结论:老年人眼部原发肿瘤的发病率与普通人群及儿童有明显的差异,而且随着年龄增大,恶性肿瘤比例有增高趋势。

AIM：To analyze the composition, distribution and characteristics of the elderly primary ocular tumors. METHODS： This was a retrospective study and all 504 cases with primary ocular tumors aged 60 years or older were collected in Shanxi Eye Hospital, during the year 2000-2012. The onset age, location and pathological pattern were analyzed.RESULTS： There were 346 cases of benign ocular tumors（68.7%）, and 158 cases of malignancy（31.3%）.Papillomas was the most common type of the benign with 83 cases（16.5%）, followed by a variety of inflammatory cysts and lesions with 69 cases（13.7%）and 64 cases（12.7%）respectively. Among malignant tumors cases, eyelid basal cell carcinoma originated from epithelial was the most common with 72 cases（14.3%）, followed by skin appendages sources malignant tumors with 39 cases（7.7%）. Concerning the location of ocular tumors, there were 282 cases of eyelid tumor（56.0%）occupied the first position followed by conjunctival tumor with 157 cases（31.2%）. CONCLUSION： The prevalence and type of primary ocular tumor in elderly people are significant differences from the general population and children＇s, and the proportion of malignant tumors tended to increase along with the increase of age.