氩离子凝固术在食管狭窄中的应用

Application of argon plasma coagulation in treatment of esophageal strictures

目的:探讨氩离子凝固术在食管狭窄中的应用价值.方法:通过对112例短段食管狭窄及支架置入术后再狭窄的对照研究,比较氩离子凝固术与单纯探条扩张术组及氩离子凝固术与二次支架置入术组吞咽困难缓解情况.结果:氩离子凝固术组在3 mo和6 mo的随访期有效率高于单纯探条扩张术组(68.57%vs42.86%,P<0.05)和(34.29%vs 10.71%,P<0.05),差异有统计学意义;氩离子凝固术与二次支架置入术在1 mo和3 mo随访期差异无统计学意义,6 mo二次支架置入术效果好于氩离子凝固术(50.00%vs 21.74%,P<0.05).结论:内镜下氩离子凝固术能有效解除短段的食管狭窄及支架置入术后再狭窄,是一种安全有效的方法.

AIM： To assess the application value of argon plasma coagulation in the treatment of esophageal strictures. METHODS： A comparative study of 112 patients with short-segment esophageal stenosis or in-stent restenosis was performed. The relief of dysphagia was compared between an argon plasma coagulation group and a simple bougie dilatation group or between an argon plasma coagulation group and a second stenting group. RESULTS： The response rates in the argonplasma coagulation group was significantly better than those in the simple bougie dilatation group during follow-up periods of 3 months （68.57% vs 42.86%, P 〈 0.05） and 6 months （34.29% vs 10.71%, P 〈 0.05）. The response rates in the argon plasma coagulation group and second stenting group were not statistically significant during follow-up periods of I and 3 months, but the response rate in the second stenting group was better after 6 months （50.00% vs 21.74%, P 〈 0.05）. CONCLUSION： Endoscopic argon plasma coagulation can effectively relieve short-segment esophageal stenosis and restenosis after stenting, representing a safe and effective method.