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成骨细胞粘附中整合素机制的研究进展 被引量：3

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摘要 种植体/骨界面新骨生长方式分为远端成骨和接触成骨两种,普遍认为接触成骨更能解释骨整合界面的理想状态。骨中包含多种类型的细胞,成骨细胞是骨形成的主要功能细胞,其分泌类骨质（骨基质未矿化的有机成分）,随着类骨质的沉积、矿化,成骨细胞陷入骨陷窝,成为骨衬里层细胞或发生凋亡[1]。
作者 路萌萌 周延民 赵静辉
机构地区 吉林大学口腔医学院种植中心
出处 《口腔医学研究》 CAS CSCD 2014年第5期479-481,共3页 Journal of Oral Science Research
基金 国家自然科学基金青年基金(编号:81200809) 高等学校博士学科点专项科研基金(编号:20120061110077)
关键词 成骨细胞粘附 整合素 骨整合界面 生长方式 有机成分 类骨质 骨界面 种植体
分类号 R783.6 [医药卫生—口腔医学]
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参考文献30

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同被引文献22

  • 1戚孟春,胡静,韩立赤,邹淑娟,王大章.成骨细胞在机械力刺激下细胞骨架及细胞形态改变的体外研究[J].中国口腔颌面外科杂志,2004,2(3):181-184. 被引量：16
  • 2Lira YJ, Oshida Y, Andre CJ, et al. Surface characterization of variously treated titanium materials [J]. Int J Oral Maxil- lofac Implants, 2001, 16 : 333--42.
  • 3Zhu X, Chen J, Scheideler L, et al. Effects of topography and composition of titanium surface oxides on osteoblast re- sponses [J]. Biomaterials, 2004, 25(18) : 4087--103.
  • 4Liu H, Webster TJ. Nanomedieine for implants: A review of studies and necessary experimental tools [J]. Biomaterials, 2007, 28 ; 354--369.
  • 5Kim MJ, Kim CW, Lim YJ, et al. Microrough titanium sur- face affects biologic response in MG63 osteoblast--like cells [J]. J Biomed Mater Res A, 2006, 79 : 102332.
  • 6Saito T, Hayashi H, Kameyama T, et al. Suppressed prolif- eration of mouse osteoblast--like ceils by a rough--surfaced substrate leads to low differentiation and mineralization [J]. Mater Sci Eng C, 2010, 30 : 1--7 ISO10993--12:2012.
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  • 9Liu X, Li X, Li S, et al. An in vitro study of a titanium sur- face modified by simvastatin--loaded titania nanotubes--mi- celles [J]. Journal of biomedical nanotechnology, 2014, 10 (2) : 194--204.
  • 10Schwartz Z, Olivares--Navarrete R, Wieland M,etal. Mech- anisms regulating increased production of osteoprotegerin by osteoblasts cultured on microstructured titanium surfaces [J]. Biomaterials, 2009, 30 : 3390--6.

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口腔医学研究
2014年 第5期

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