Prestige LP人工椎间盘置换治疗单节段颈椎病的近期疗效

The short-term efficacy of Prestige LP artificial disc single-level replacement for cervical spondylosis

目的探讨应用Prestige LP人工椎间盘置换治疗单节段颈椎病的近期临床疗效。方法治疗单节段颈椎病患者15例,统计并分析患者术前和术后1、3、12个月随访时JOA评分、NDI脊髓功能评分、颈部及上肢疼痛VAS评分、置换节段活动度、颈椎运动范围、颈椎生理曲度等指标。结果神经系统症状均有不同程度改善,术后1、3个月及12个月时颈椎生理曲度较术前比均有显著性差异(P<0.05)。术后1、3个月及12个月时颈椎的总活动度、置换节段活动度基本恢复至术前水平,二者无显著性差异(P>0.05)。所有患者均未发生脊髓及神经根损伤、假体移位或异位骨化等并发症。结论应用Prestige LP人工椎间盘置换术治疗单节段颈椎间盘退变性疾病早期临床疗效良好,中远期疗效有待进一步观察。

Objective To evaluate the short-term radiological and functional outcome of artifi-cial disc single-level replacement for cervical disc degenerative diseases. Methods 15 patients with cervical disc degenerative diseases underwent Prestige LP artificial disc replacement were se-lected in this study. There were 8 cases of cervical spondylotic myelopathy and 7 cases of nerve root cervical syndrome. The range of motion（ROM） of the cervical spine,ROM of treated segment and lordosis of cervical spine were reviewed respectively at preoperation and 1 month,3 months and 12 months postoperation,and the NDI scores,VAS for neck and arm pain were also reviewed respectively preoperation and the last follow-up. Results At an average of 16.3 months（range 6-24 months） follow-up,the neurologic symptom and sign in all cases had significant improvement. The NDI was significantly improved from（47.80＆#177;11.52）% to（16.20＆#177;9.34）%（P＆lt;0.05）,the VAS for neck and arm pain were all significantly improved from（5.13＆#177;1.44） and （6.30＆#177;1.51） to （1.46＆#177;0. 81） and （1.14 ＆#177;0.57） respectively （P＆lt;0.05）. The lordosis of cervical spine was significantly in-creased at follow up （P＆lt;0.05）. The ROM of the cervical spine and ROM of treated segment re-covered to the preoperative level. There was no neurological complication during operation,and no ossification in the replaced level and no prosthesis displacement and loosening . Conclusion Our findings suggest that the Prestige LP cervical disc replacement in the treatment of cervical disc degenerative diseases has good functional short-term results, further follow-up is necessary to e-valuate mid- and long-term outcome.