期刊文献+

右美托咪啶对单肺通气麻醉患者肺缺血-再灌注的影响 被引量:2

下载PDF
导出
摘要 目的探讨右美托咪啶对单肺通气麻醉患者肺缺血-再灌注的影响。方法 40例择期行食管癌根治术患者随机分为2组,对照组20例在异丙酚和瑞芬太尼维持麻醉的基础上静脉输注生理盐水,观察组20例在异丙酚和瑞芬太尼维持麻醉的基础上静脉输注右美托咪啶,观察比较2组患者单肺通气时肺缺血-再灌注情况。结果相对于对照组,观察组患者的血清髓过氧化物酶、黄嘌呤氧化酶活性得到有效抑制,且中性粒细胞计数出现较大幅度升高。结论右美托咪啶对单肺通气麻醉患者肺缺血-再灌注损伤有积极保护作用。
作者 刘渊泉
出处 《现代中西医结合杂志》 CAS 2014年第17期1905-1906,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
  • 相关文献

参考文献9

二级参考文献99

  • 1王刚,陈婷婷,高长青.乌司他丁对创伤失血性休克兔肺损伤的保护作用[J].中国危重病急救医学,2005,17(1):36-38. 被引量:25
  • 2刘勇,陈锋,朱涛,王焱林.单肺通气时小潮气量对血气和血流动力学的影响[J].郧阳医学院学报,2006,25(1):34-35. 被引量:3
  • 3周建明,刘志勇,贾辉.乌司他丁对犬肺缺血再灌注损伤的保护作用[J].江苏医药,2007,33(4):378-380. 被引量:5
  • 4Licker M,de Perrot M, Spiliopoulos A, et al. Risk factors for acute lung injury after thoracic surgery for lung cancer. Anesth Analg, 2003,97 : 1558 1565.
  • 5Goldblum SE, Wu KM, Jay M. Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits. J Appl Physiol, 1985,59 : 1978-1985.
  • 6Glasser SA, Domino KB, Lindgren L, et al. Pulmonary blood pressure and flow during ate;ectasos in the dog. Anesthesiology, 1983,58 : 225-231.
  • 7Zhang H,Downey GP, Suter PM, et al. Conventional mechanical ventilation is associated with bronchoalveolar lavage- induced activation of polymorphonuclear leukoeytes:a possible mechanism to explain the systemic consequences of ventilatorinduced lung injury in patients with ARDS. Anesthesiology, 2002,97 : 1426-1433.
  • 8[1]Khan ZP,Ferguson CN,Jones RM.Alpha-2 and imidazoline receptor agonists:their pharmacology and therapeutic role[J].Anesthesia,1999;54:146-165.
  • 9[2]Kamibayashi T,Maze M.Clinical uses of alpha 2-adrenergic agonists[J].Anesthesiology,2000;93:1345-1350.
  • 10[3]Calzada BC,De Artinano AA.[alpha]2-Adrenoreceptor subtypes[J].Pharmacol Res,2001;44:195-208.

共引文献793

同被引文献34

  • 1Stefan Hofer,Jochen Steppan,Tanja Wagner,Benjamin Funke,Christoph Lichtenstern,Eike Martin,Bernhard M Graf,Angelika Bierhaus,Markus A Weigand.Central sympatholytics prolong survival in experimental sepsis. Journal of Critical Care . 2009
  • 2Takumi Taniguchi,Yoko Kidani,Hiroko Kanakura,Yasuhiko Takemoto,Ken Yamamoto.Effects of dexmedetomidine on mortality rate and inflammatory responses to endotoxin-induced shock in rats[J]. Critical Care Medicine . 2004 (6)
  • 3Chih-Lin Yang,Pei-Shan Tsai,Chun-Jen Huang.??Effects of Dexmedetomidine on Regulating Pulmonary Inflammation in a Rat Model of Ventilator-induced Lung Injury(J)Acta Anaesthesiologica Taiwanica . 2008 (4)
  • 4J. Gu,J. Chen,P. Xia.Dexmedetomidine attenuates remote lung injury induced by renal ischemia-reperfusion in mice. Acta Anaesthesiologica Scandinavica . 2011
  • 5Hong Qiao,Robert D Sanders,Daqing Ma,Xinmin Wu,Mervyn Maze.Sedation improves early outcome in severely septic Sprague Dawley rats. Journal of Critical Care . 2009
  • 6Constantinos Chrysostomou,Carol G Schmitt.Dexmedetomidine: sedation, analgesia and beyond. Expert Opinion on Drug Metabolism and Toxicology . 2008
  • 7The protective effects of dexmedetomidine on the liver and remote organs against hepatic ischemia reperfusion injury in rats(J)International Journal of Surgery . 2012
  • 8Chih-Lin Yang,Cay-Huyen Chen,Pei-Shan Tsai,Tao-Yeuan Wang,Chun-Jen Huang.??Protective Effects of Dexmedetomidine-Ketamine Combination Against Ventilator-Induced Lung Injury in Endotoxemia Rats(J)Journal of Surgical Research . 2011 (2)
  • 9Chen-Hsien Yang,Pei-Shan Tsai,Tao-Yeuan Wang,Chun-Jen Huang.??Dexmedetomidine–ketamine combination mitigates acute lung injury in haemorrhagic shock rats(J)Resuscitation . 2009 (10)
  • 10Takumi Taniguchi,Akihide Kurita,Kyoko Kobayashi,Ken Yamamoto,Hideo Inaba.??Dose- and time-related effects of dexmedetomidine on mortality and inflammatory responses to endotoxin-induced shock in rats(J)Journal of Anesthesia . 2008 (3)

引证文献2

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部