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不同年龄段直肠癌临床特征比较 被引量:14

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摘要 目的探讨不同年龄段直肠癌临床特征的差异。方法将1 074例直肠癌患者分为青年、中年及老年3个年龄段,比较该3个年龄段直肠癌临床特征的差异。结果青年、中年和老年直肠癌患者所占比例分别为13.6%、29.1%和57.4%。青年、中年和老年患者男性所占比例分别为52.7%、59.6%和62.0%,男女性别差异无统计学意义(P=0.118);便血(43.0%)、腹泻(30.0%)和腹痛(11.7%)为所有患者的主要临床症状;随着发病年龄增加,腺癌在青年(81.5%)、中年(92.0%)和老年(95.0%)所占比例呈升高趋势(C=0.178,P<0.05),且高分化腺癌的比例逐渐上升,年龄与直肠腺癌分化程度呈正相关(rs=0.169,P<0.05);青年患者组织学类型恶性程度高的比例(44.5%)高于中年组(36.5%)及老年组(25.8%)(P<0.001),年龄与直肠癌恶性程度呈负相关(rs=-0.150,P<0.05)。青年患者肿瘤病灶下缘距肛缘距离[(7.4±3.7)cm]较中年组[(7.8±3.8)cm]和老年组[(8.3±3.9)cm]更近(P=0.04),年龄与直肠癌下缘距肛缘距离呈正相关(r=0.102,P=0.001)。结论直肠癌更多见于男性患者,年轻患者的组织学恶性程度更高,更容易发生低位直肠癌。
出处 《广东医学》 CAS CSCD 北大核心 2014年第10期1569-1571,共3页 Guangdong Medical Journal
基金 广东省自然科学基金资助项目(编号:9151008004000014)
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共引文献17

同被引文献160

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