摘要
目的探讨对支气管镜毛刷标本进行液基薄层细胞学制片技术(LCT)在肺癌细胞诊断中的应用价值。方法收集252例肺癌患者的支气管镜刷检标本,同时进行LCT和直接涂片法检测,比较两种方法的涂片质量及诊断的阳性率。结果 LCT检测的标本切片质量高,LCT诊断肺癌的敏感度为58.33%。直接涂片法诊断肺癌的敏感度为33.19%。LCT的敏感度高于直接涂片法(P<0.05)。结论 LCT液基薄层细胞学制片技术在支气管镜刷检细胞学标本制片质量及诊断准确性明显高于传统涂片方法,支气管镜刷检标本的LCT检测可推广应用于临床。
Objective To explore the clinical value of liquid-based cytology test （ LCT ） in cytological screening of bronchial brushing for the diagnosis of lung cancer. Methods The bronchial brushing specimens of 252 patients who were diagnosed as lung cancer were collected. The diagnostic sensitivity and cytological findings of LCT were compared with those of conventional smear （ CS） method for diagnosing lung cancer. Results LCT slides showed decreased areas of cell monolayers. LCT had a significantly higher diagnostic sensitivity for lung cancer （58. 33%） than CS method did （33. 19%, P〈0. 05）. Conclusion LCT in cytological screening of bronchial brushing has higher diagnostic value of lung cancer and it can be easily performed.
出处
《临床肺科杂志》
2014年第7期1308-1309,1314,共3页
Journal of Clinical Pulmonary Medicine
关键词
肺癌
支气管镜刷检标本
LCT
传统涂片法
lung cancer
bronchial brushing
liquid-based cytology test
conventional smear
