子宫内膜异位症伴不孕65例临床分析

Clinical analysis of endometriosis associated with infertility

目的：探讨子宫内膜异位症（简称内异症）伴不孕影响治疗效果的因素及治疗方案。方法对该院妇产科住院治疗65例内异症伴不孕患者的临床资料进行回顾性分析。结果内异症Ⅰ～Ⅱ期患者治疗后妊娠率为58.8％，显著高于Ⅲ～Ⅳ期患者的妊娠率（19.4％）（ P＜0.01）；以单纯卵巢巧克力囊肿为病变部位的妊娠率为48.0％，高于其他部位的妊娠率（13.3％）（ P ＜0.05）；继发性不孕患者治疗后妊娠率为56.0％，高于原发性不孕的妊娠率（30.0％）（ P＜0.05）。结论内异症伴不孕的治疗效果与患者病变程度、病变部位、不孕类别等因素有关；采用孕激素-手术-孕激素是治疗内异症伴不孕的有效方案。

Objective To explore the influence factors of treatment effect and the treatment schemes of en-dometriosis with infertility .Methods The clinical data of 65 inpatients with endometriosis and infertility treated in department of gynaecology and obstetrics of the Sixth People′s Hospital were analyzed retrospectively .Results After treatment,the pregnancy rate in patients with stageⅠ~Ⅱ of endometriosis（58.8%） was significantly higher than that in patients with stage Ⅲ~Ⅳ（19.4%）（P〈0.01）;The pregnancy rate in patients with simple ovarian chocolate cyst as lesion site（48.0%） was higher than that in patients with other lesion site （13.3%）（P〈0.05）; The preg-nancy rate of patients with secondary infertility （ 56.0%） was higher than that patients with primary infertility （30.0%）（P〈0.05）.Conclusion The treatment effects of endometriosis with infertility have associated with lesion degree, lesion location and categories of infertility; Progesterone-operation-progesterone therapy is effective in trea-ting patients with endometriosis associated with infertility .