HSP47与宫腔粘连的关系及在纤维化疾病中的意义

The Relationship between HSP47 and Intrauterine Adhesions and Its Significance in Fibrosis Diseases

目的:综述HSP47在纤维化疾病中的意义,探索宫腔粘连的发病机制。方法:对HSP47在肝纤维化、肺纤维化、肾纤维化、皮肤瘢痕等纤维化疾病中的意义进行探讨,探索其与宫腔粘连的关系。结果:HSP47在纤维化疾病中高表达,与宫腔粘连的发生存在某种关系。结论:对宫腔粘连的发病机制进行探讨和展望。

Objective：To review the significance of HSP47 in fibrosis disease and explore the pathogenesis of intrauterine adhesions. Methods：The significance of HSP47 in fibrosis diseases such as liver fibrosis,pulmonary fibrosis,renal fibrosis and skin scar was discussed,and the relationship between HSP47 and intrauterine adhesions was explored. Results：HSP47 was high expression in fibrosis disease,and there was relationship between HSP47 and intrauterine adhesions. Conclusion：The relationship between HSP47 and intrauterine adhesion are discussed.