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药物代谢酶遗传多态性与合理用药研究进展

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摘要 近年来,随着人们对医疗质量需求的提高,治疗上的量体裁衣,一人一方,也就是用药的个体化越来越受到重视,客观上要求医师应该了解患者的药物遗传特征,以便利用遗传药理学知识高质量地指导合理用药。
作者 周青 刘卫
出处 《实用医药杂志》 2014年第5期455-458,共4页 Practical Journal of Medicine & Pharmacy
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  • 1Mega JL,Close SL,Wiviott SD,et al.Cytochrome P450 genetic polymorphisms and the response to prasugrel relationship to pharmacokinetic,pharmacodynamic,and clinical outcomes[J].Circulation,2009,119(24):2553-2560.
  • 2Mayer U,Wagenaar E,Beijnen JH,et al.Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdrla P-glyco-protein [J ].British Journal of Pharmacology 2012,119(10):1038-1044.
  • 3Lin TC,Yen JM,Gong KB,et al.Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome among the Taiwan Residents population-not correlated with insulin receptor sub-strate-1 Gly972Arg/AlaS13Pro polymorphism[J].BMC Medical Genetics,2006,7(1):36.
  • 4Kolesnikov Y,Gabovits B,Levin A,et al.Combined catechol-O-methyltransferase and μ-opioid receptor gene polymorphisms affect morphine postoperative analgesia and central side effects [J].Anesthesia & Analgesia,2011,112(4):448-453.
  • 5Tilak AV,Iyer SN,Mukherjee MS,et al.Full-gene-sequencing analysis of N-acetyhransferase-2 in an adult indian population [J].Genetic Testing and Molecular Biomarkers,2012,10(1):21.
  • 6Cascorbi I.Pharmacogenetics of phase II drug metabolizing en-zymes[J].Pharmacogenetics and Individualized Therapy,2012,2(1):81-100.
  • 7Bochud M,Burnier M,Guessous I.Top three pharmacogenomics and personalized medicine applications at the nexus of renal pathophysiology and cardiovascular medicine[J].Current Phar-macogenomics and Personalized Medicine,2011,9(3):299-322.
  • 8Hiratsuka M.In vitro assessment of the allelic variants of cy-tochrome P450[J].Drug Metabolism and Pharmacokinetics,2011,11(10):240.
  • 9Yoshimoto K,Echizen H,Chiba K,et al.Identification of human CYP isoforms involved in the metabolism of propranolol enan-tiomers-N-desisopropylation is mediated mainly by CYP1A2[J].British Journal of Clinical Pharmacology,2012,39(4):421-431.
  • 10Bertilsson L,Carrillo J,Dahl M,et al.Clozapine disposition co-varies with CYP1A2 activity determined by a caffeine test[J].British Journal of Clinical Pharmacology,2012,38(4):471-473.

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