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大肠埃希菌产超广谱β内酰胺酶检出率及耐药性分析 被引量:2

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摘要 目的了解临床分离大肠埃希菌产超广谱β-内酰胺酶(ESBLs)的检出率和耐药情况,为临床合理选用抗菌药物提供依据。方法根据临床标本分离出的所有大肠埃希菌进行梅里埃ATB Expression菌种鉴定及药敏试验,并采用确证试验验证非产ESBLs菌株和产ESBLs菌株,应用梅里埃ATBplus软件进行数据分析。结果 100株大肠埃希菌中,检出产ESBLs菌48株,阳性率为48.0%;非产ESBLs菌52株,占52.0%;对13种常用抗菌药物的药敏试验结果显示,产ESBLs大肠埃希菌对亚胺培南耐药率最低,为0.00%;对头孢他啶、头孢唑林、氨苄西林、氨曲南等耐药率最高,均为100.00%;对阿奇霉素、庆大霉素、复方新诺明、氧氟沙星的耐药率均较高,分别为89.58%、91.67%、87.50%、93.75%。结论及时监测产ESBLs大肠埃希菌的发生率及耐药性,能够指导临床合理使用抗菌药物,减少ESBLs菌的产生。
机构地区 平远县人民医院
出处 《现代医药卫生》 2014年第11期1691-1692,共2页 Journal of Modern Medicine & Health
基金 广东省梅州市医药卫生科研课题(2013-B-63)
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