体检人群高尿酸血症与代谢综合征的关系分析

Analysis on Correlation Between Serum Uric Acid(SUA) and Metabolic Syndrome(MS)

目的：探讨大连体检人群血尿酸水平与肥胖、血压、血脂、血糖等代谢综合征各组分的关系。方法：随机抽选2012～2013年大连大学附属中山医院体检中心体检人群960例,检测并分析体重指数、血压、血尿酸、空腹血糖、总胆固醇、甘油三酯等指标。结果：男性和女性的高尿酸血症患病率分别为31.9%和9.6%（P〈0.01）;男性的BMI及TG随血尿酸升高而明显增高（P〈0.01）;女性BMI、SBP、DBP、TG、LDL-C、FPG随血尿酸升高而显著增高（P〈0.01）。结论：血尿酸与肥胖、高TG等代谢综合征各组分之间关系密切,控制血尿酸水平是代谢综合征防治的重要因素,也是预防心、脑血管疾病的重要环节。

Objective： To investigate correlation between serum uric acid （SUA） and metabolic syndrome （MS） in people taking physical examination in Dalian. Methods： 960 Subjects were selected randomly from people taking physical examination at PEC of affiliated Zhongshan hospital to Dalian university from 2012 to 2013. BMI indicators such as blood pressure, SUA, FPG, TC, TG were checked and analyzed. Results： The prevalence rates of hyperuricemia in male and female were 31.9 % and 9.6% respectively （P〈0.01）. BMI and TG of male subjects increased significantly with increasing level of SUA （P〈0.01）. BMI, SBP, DBP, TG, LDL-C and FPG of female subjects increased significantly with increasing level ofSUA （P〈0.01）. Conclusion： Serum uric acid is closely related to metabolic syndrome. Controlling SUA level is very important in the prevention and treatment of MS as well as cardiovascular disease and cerebrovascular disease.