无抽搐电休克治疗慢性精神分裂症伴迟发性运动障碍临床研究

A clinical study of MECT in the treatment of chronic schizo-phrenia with tardive dyskinesia

目的：探讨无抽搐电休克治疗慢性精神分裂症伴迟发性运动障碍患者的临床疗效。方法对58例慢性精神分裂症伴迟发性运动障碍患者在维持原用抗精神病药物治疗的基础上联合无抽搐电休克治疗，观察6周。采用不自主运动评定量表评定临床效果。结果本组经无抽搐电休克治疗6周后不自主运动评定量表评分较治疗前显著下降（ t＝18．34，P＜0．01），不自主运动症状明显改善，总有效率达93．1％。结论无抽搐电休克治疗能显著改善慢性精神分裂症伴迟发性运动障碍患者的不自主运动症状。

Objective To explore the efficacy of modified electroconvulsive thera-py （MECT） in the treatment of chronic schizophrenia with tardive dyskinesia （TD） .Methods Fifty-eight chronic schizophrenics with TD were treated with MECT on the basis of maintaining antipsychotic treat-ment for 6 weeks .Efficacies were assessed with the Abnormal Involuntary Movement Scale （AIMS） .Re-sults After 6-week MECT the AIMS score lowered more significantly compared with pre-treatment （t=18 .34 ,P〈 0 .01） ,involuntary movement symptoms improved notably ,total effective rate was 93 .1% . Conclusion MECT could improve involuntary movement symptoms of chronic schizophrenic with TD sig-nificantly .