摘要
采用试管稀释法和纸片法测定 9株乳房链球菌对克林霉素的耐药性 ,通过PCR反应检测克林霉素的耐药性基因 ,并进行测序比较。发现克林霉素对乳房链球菌的抗菌活力较强 ,克林霉素耐药基因同时存在于乳房链球菌的染色体和质粒上。
A total 9 isolates of the Streptococcus uberis were tested for minimal inhibitory concentration (MIC)and antibiotic susceptibility to clindamycin by using test_tube dilution and disc diffusion methods.PCR was used to detect the erm gene in Streptococcus uberis.We find that clindamycin has strong antibacterial activities.Comparision of erm (S.uberis)and ermS(S.sanguis)sequences showed 99%(750/757)conservation,which also suggests erm gene located on both plasmid and chromosome.
出处
《中国预防兽医学报》
CAS
CSCD
北大核心
2001年第2期134-136,共3页
Chinese Journal of Preventive Veterinary Medicine