生姜内酯的分离与结构表征

Isolation and Structure Characterization of Zingiberolide

从荜澄茄药材粗粉中分离得生姜内酯晶体(1),其结构经NMR和X-射线单晶衍射分析确证。1的晶体为单斜晶系,空间群P21/c,晶胞参数a=8.780 9(5),b=19.923 9(9),c=7.139 1(4),β=107.299(6)°,V=1 192.49(10)3,Z=4,F(000)=512.0,R1=0.049 3,wR2=0.109 4。1为首次从樟科植物中发现,由于其具有罕见的三环骈双内酯结构,其完整的结构表征对类似化合物的结构鉴定具有重要的参考价值。

Zingiberolide（1） was isolated from Litseae Fructus.The structure was confirmed by NMR and X-ray single crystal diffraction.The crystal of 1 belongs to monoclinic system,space group P21/cwith a =8.780 9（5） （A）,b =19.923 9（9） （A）,c =7.139 1（4） （A）,β=107.299（6）°,V=1 192.49 （10） （A）3,Z=4,F（000） =512.0,R1 =0.049 3,wR2 =0.109 4.1 was firstly found from Lauraceae family.Because the rare tricyclic parallel dilactone structure of 1,the detail characterization is valuable for similar nature products.