摘要
目的探讨医院人群血清乙型肝炎病毒(HBV)血清学标志物的分布特征,为乙型肝炎预防与控制提供依据。方法收集接受HBV血清学检测的医院人员11 210例,将其按年龄分为:〉0~25岁组(n=3 553)、〉25~50岁组(n=7 651)。采用酶联免疫吸附测定(ELISA)及Roche Cobas E601型全自动电化学发光免疫分析仪检测血清HBV表面抗原(HBsAg)、抗HBV表面抗体(HBsAb)、HBV e抗原(HBeAg)、抗HBV e抗体(HBeAb)及抗HBV核心抗体(HBcAb)。结果 〉0~25岁组、〉25~50岁组受检者HBsAg阳性率分别为16.16%、21.19%。总体HBsAg、HBsAb阳性率及全阴性率为19.59%(2 195/11 204)、37.02%(4 148/11 204)及11.84%(1 327/11 204)。结论医院人群血清HBV标志物分布特征可为采取有效的乙型肝炎防控措施提供了可靠依据。
Objective To investigate the distribution characteristics of serum hepatitis B virus (HBV) markers of population in hospital and to provide the basis for prevention and control of virus B hepatitis .Methods 11 210 people in hospital who had accepted HBV serological testing were enrolled ,and were divided into 〉0 -25-year old group(n=3 553) and 〉25 -50-year old group(n=7 651) according to their ages .Enzyme-linked Immunosorbent Assay(ELISA) and Roche Cobas E601 Automatic Electro-chemiluminescence immunoassay analyzer were employed to detect serum HBV surface antigen (HBsAg ) ,anti-HBV surface anti-body(HBsAb) ,HBV e antigen(HBeAg) ,anti-HBV e antibody(HBeAb) and anti-HBV core antibody(HBcAb) .Results HBsAg positive rates of subjects in 〉 0 -25-year old group and 〉 25 -50-year old group were 16 .16% and 21 .19% ,respectively .The overall positive rates of HBsAg and HBsAb and full-negative rate were 19 .59% (2 195/11 204) ,37 .02% (4 148/11 204) and 11 .84% (1 327/11 204) ,respectively .Conclusion Distribution characteristics of HBV markers of population in hospital may pro-vide a reliable basis for taking effective protective and control measures against virus B hepatitis .
出处
《国际检验医学杂志》
CAS
2014年第10期1263-1265,共3页
International Journal of Laboratory Medicine
关键词
肝炎病毒
乙型
生物学标记
医院
hepatitis B virus
biological markers
hospital