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NGAL临床应用及实验室检测最新进展 被引量:8

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摘要 中性粒细胞明胶酶相关脂质运载蛋白(neutrophil gelatinase-associated lipocalin,NGAL)属于脂质运载蛋白家族成员。NGAL cDNA及其全基因序列分别于1994、1997年被克隆鉴定[1]。近年来,NGAL基因的功能及其在人体正常和肿瘤组织中的表达特征受到关注,并且在肾脏疾病、肿瘤等发病机制的相关研究中取得了一些有意义的进展,现就其生物学特性、
作者 刘琴 蒋洪敏
出处 《国际检验医学杂志》 CAS 2014年第10期1302-1304,共3页 International Journal of Laboratory Medicine
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  • 1RL Mehta,JA Kellum,S Shah,B Molitoris,C Ronco,D Warnock,A Levin,王欣.急性肾损伤诊断与分类专家共识[J].中华肾脏病杂志,2006,22(11):661-663. 被引量:356
  • 2杨静华,刘建辉,孙志平,肖玉兰.血清骨桥蛋白和CA_(125)联合检测在卵巢上皮癌诊疗中的应用价值[J].河北医药,2007,29(6):549-551. 被引量:11
  • 3Buoro S, Gustinetti R, Dominoni P, et al. Analytical evaluation of Sysmex UF-1000i for flow cytometric analysis of peritoneal fluid [ J]. Clin Biochem,2012,45 ( 15 ) : 1263-1265.
  • 4Axelsson L, Bergenfeldt M, Ohlsson K. Studies of the release and turnover of a human neutrophil lipocalin [ J ]. Scand J Clin Lab Invest, 1995,55 ( 3 ) : 577-588.
  • 5Martino FK, Filippi I, Giavarina D, et al. Neutrophil gelatinase-as- sociated lipocalin in the early diagnosis of peritonitis:the case of neutrophil gelatinase-associated lipocalin [J]. Contrib Nephrol, 2012,178(2) :258-263.
  • 6Leung JC, Lam MF, Tang SC ,et al. Role of neutrophil gelatinase- associated lipocalin in continuous ambulatory peritoneal dialysis- related peritonitis [ J ]. J Clin Immunol,2009,29 ( 12 ) :365-378.
  • 7Lippi G, Plebani M. Neutrophil gelatinase-associated lipocalin (NGAL) :the laboratory perspective [ J]. Clin Chem Lab Med, 2012,50(9) :1483-1487.
  • 8Clerico A, Galli C, Fortunato A, et al. Neutrophil gelatinase-asso- ciated lipocalin (NGAL) as biomarker of acute kidney injury : a review of the laboratory characteristics and clinical evidences [J]. Clin Chem Lab Med,2012,50(9) :1505-1517.
  • 9Makris K, Rizos D, Kafkas N, et al. Neurophil gelatinase-associat- ed lipocalin as a new biomarker in laboratory medicine[ J]. ClinChem Lab Med,2012,50(9):1519-1532.
  • 10Martensson J, Xu S, Bell M, et al. Immunoassays distinguishing between HNL/NGAL released in urine from kidney epithelial cells and ueutrophils[ J ]. Clin Chim Acta, 2012,413 ( 19/20 ) : 1661-1667.

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