维生素D缺乏与T淋巴细胞对小儿腹泻的影响因素分析

The Analysis of the Deficiency of Vitamin D and T Lymphocyte Effect on Infantile Diarrhea Factors

目的:维生素D缺乏与T淋巴细胞对小儿腹泻的影响因素进行分析讨论。方法:选取2010年4月-2012年4月到笔者所在医院就诊的小儿腹泻患儿122例作为研究对象。患儿确诊为小儿腹泻后入院,进行患儿病情询问调查,包括年龄、病程、家族遗传病史、有无过敏史等,随后送标本入医院检验科进行常规检验和针对性小儿腹泻的便常规检验,统计记录数据,进行分析比较。结果:通过回顾分析试验报告发现,在122例小儿腹泻患儿中,有83例(68.04%)患儿是非感染性腹泻,感染性腹泻39例(31.97%),比较差异有统计学意义(P<0.05)。而在这122例患儿中有113例患儿(92.63%)有维生素D缺乏和116例(95.09%)患儿有T淋巴细胞亚群减少的现象。结论:小儿腹泻中非感染性因素占绝大多数,小儿腹泻可能与维生素D缺乏以及T淋巴细胞亚群的减少有关。

Objective：To discuss the lack of vitamin D and T lymphocyte effect on infantile diarrhea factors.Method：One hundred and tenty-two cases of children with infantile diarrhea as the research object were chosen in the hospital from April 2010 to April 2012.Children admitted to hospital after diagnosis of infantile diarrhea,children were asked to investigate the disease,including age,course of the disease,family history,any allergies,etc,then admitted to the hospital clinical laboratory for routine inspection and the stool routine inspection of infantile diarrhea,statistical data,carries on the analysis comparison. Result：Through the review and analysis experiment report in 122 cases of children with diarrhea,83 cases（68.04%） of non-infectious diarrhea in children,39 cases（31.97%） of infectious diarrhea in children,and the difference was statistically significant（P〈0.05）. There were 113 cases in 122 cases（92.63%） had a vitamin D deficiency and 116 cases（95.09%） phenomenon of T lymphocyte subsets decreased. Conclusion：Non-infectious factors accounted for the vast majority of children with diarrhea,infantile diarrhea may be related with vitamin D deficiency and reduced T lymphocyte subsets.