妊娠期高血压疾病患者血液指标变化的临床指导价值

Clinical Guidance Value of Blood Parameters Changes in Patients with Hypertensive Disorders in Pregnancy

目的:研究妊娠期高血压疾病患者血液指标变化的临床指导价值。方法:将2012年3月-2013年6月笔者所在医院收治的妊娠期高血压疾病患者纳入观察组,同期在笔者所在医院接受产前检查的健康孕妇纳入对照组,检测两组产妇的血液指标血管内皮生长因子(VEGF)和胎盘生长因子(PLGF)的含量,并分析其与血压水平的相关性。结果:(1)观察组产妇血液中VEGF和PLGF的含量均低于对照组;(2)血液中VEGF和PLGF的含量与收缩压、舒张压水平呈负相关。结论:妊娠期高血压疾病产妇的血液中VEGF和PLGF含量降低,且与血压水平呈现较好的相关性,具有积极的临床指导价值。

Objective：To study the clinical value of blood parameters change in patients with hypertensive disorders in pregnancy.Method：Patients with hypertensive disorders in pregnancy from March 2012 to June 2013 in our hospital were selected as observation group,at the same period in our hospital healthy pregnant woman were selected as control group,maternal blood indicators of vascular endothelial growth factor （VEGF） and placental growth factor （PLGF） levels were detected,and to analyze its correlation with blood pressure levels.Result：（1）Maternal blood levels of VEGF and PLGF were lower in the observation group than that in the control group.（2）There was negative correlation between the blood levels of VEGF,PLGF and the levels of systolic blood pressure,diastolic blood pressure.Conclusion：Blood levels of VEGF and PLGF reduce in patients with hypertensive disorders in pregnancy is low,and it shows good correlation with blood pressure levels.There is a positive clinical guidance value.