中药油剂对气管插管全麻呼吸道并发症的预防效果评价

Preventive Effect of Traditional Chinese Medicine Oil Prescription for Throat Complications after Endotracheal Intubation under General Anesthesia

目的:探讨中药油剂对气管插管全麻呼吸道并发症的预防效果。方法:160例全麻下器官插管手术患者随机分为观察组和对照组,分别给予中药油剂咽喉喷入和布地奈德混悬液雾化吸入,比较两组患者咽喉部并发症的发生情况。结果:术后1 h,两组患者咽痛评分、咳嗽评分、声嘶评分、咽喉黏膜反应差异无统计学意义(P>0.05),术后24 h,观察组咽痛评分(1.86±0.27 VS 2.74±0.41,t=16.03,P<0.001)、声嘶评分(2.02±0.99 VS 2.84±1.04,t=5.11,P<0.001)、咽喉黏膜反应评分(0.76±0.38 VS 1.09±0.30,t=6.10,P<0.001)均低于对照组,咳嗽评分(1.21±0.48)与对照组(1.30±0.40)间差异无统计学意义(t=1.29,P=0.116);观察组与对照组总有效率分别为93.75%、90.00%,差异无统计学意义(χ2=0.125,P=0.263)。结论:中药油剂可减少气管插管后呼吸道并发症的发生,且效果持久。

Objective ： To investigate the preventive effect of traditional Chinese medicine oil prescription on relieving postoperative throat complications after endotracheal intubation under general anesthesia. Methods ： 160 patients with surgery performed endotracheal intubation under general anesthesia were randomly divided into observation group and control group and the two groups respectively were sprayed with traditional Chinese medicine oil prescription and budesonide budesonide inhalation suspension into the throat. The postoperative throat complications of two groups were compared. Results ： The sore throat, cough score, score hoarseness, throat mucositis had no statistical difference between two groups at 1 hour after operation （ P 〉 0.05 ） ; after 24 h, the sore throat score （ 1.86 ±0.27 VS 2.74 ± 0.41, t = 16.03,P 〈 0. 001 ） , hoarseness score （2.02 ± 0.99 VS 2.84 ± 1.04, t = 5.11, P 〈 0.001 ）, throat mucositis score （0.76 ± 0.38 VS 1.09 ± 0.30, t = 6.10 ,P 〈 0. 001 ） in observation group were lower than those of the control group and there was no statistical significance in cough score （ 1.21 ± 0.48 VS 1.30 ± 0.40, t = 1.29,P = 0.116） ： the total effective rates of observation group and control group were 93.75% ,90.00% respectively and the difference was not statistically significant （x^2 = 0. 125, P = 0. 263 ）. Conclusion： Traditional Chinese medicine oil prescription can reduce the throat complications resulted from endotracheal tube and the effect is lasting.