血必净注射液对感染性疾病的临床应用研究进展

Research progresses of Xuebijing injection clinical application of inflammatory diseases

血必净注射液是一种中药复方注射液,主要有效成分有红花、赤芍、川芎、丹参、当归等,其抑制炎性因子如白细胞介素、肿瘤坏死因子等表达,从而产生抗炎作用;也可以抑制炎症反应过程中的转录因子的活性,保护机体重要器官。自面世以来,在临床上广泛应用于脓毒症、多器官功能障碍综合征等,其与血必净注射液抑制炎性反应有关。

Xuebijing （XBJ） injection is a traditional Chinese medicine （TCM） injection. The injection combines five TCMs, including Carthami Flos, Paeoniae Radix Rubra, Chuanxiong Rhizoma, Salviae miltiorrhizae and Angelicae Sinensis Radix. It plays an anti - inflammatory effect by inhibiting interleukins, tumor necrosis factor and inhibiting the activity of important transcription factors, thus plays a protective role for vital organs. XBJ is widely used in the treatment of sepsis and multiple organ dysfunction syndromes; it has a close relationship with XBJ injection and the inflammatory response.