耳穴按压对大鼠精神性疲劳影响的实验研究

Experimental Study on Mental Fatigue of Rats by Auricular Acupressure Pressing

目的:探究耳穴按压对大鼠精神疲劳的治疗作用。方法:将60只Wistar大鼠随机分为空白组、单纯抓取组、模型组及耳穴按压组,每组15只。检测各组大鼠自发活动度(爬格数和探身数)、负重游泳时间。结果:与空白组对照比较,模型组的自发活动度显著减弱(P<0.05),负重游泳时间显著缩短(P<0.05),说明造模成功;与空白组对照比较,单纯抓取组的自发活动度无显著变化(P>0.05),负重游泳时间无显著延长或缩短(P>0.05),说明单纯抓取对大鼠没有治疗作用;与模型组对照比较,耳穴按压组的自发活动度显著增强(P<0.05),耳穴按压组的负重游泳时间显著延长(P<0.05),说明耳穴按压对模型大鼠具有一定的治疗作用。结论:按压耳穴可显著改善大鼠精神性疲劳的症状和体征。

Objective ：To study the therapeutic effects on mental fatigue of rats by auricular acupressure pressing. Methods：Sixty wistar rats were randomly divided into four groups （n = 15 ） ： normal group, grabbing only group, model group, and auricular acupressure pressing group. Spontaneous activity and time of loaded - swimming were measured. Results： Compared with normal group, frequency of spontaneous movement in model group was significantly reduced （ P 〈 0.05 ） ; the time of loaded - swimming was shortened significantly （ P 〈 0. 05 ）. It proved the success of modeling. Compared with normal group, there was no significant difference on frequency of spontaneous movement （ P 〉 0.05 ） and the time of loaded - swimming （ P 〉 0.05 ） in grabbing only group, which meant grabbing had no effects on mental fatigue of rats. Compared with model group, frequency of spontaneous movement in model group was significantly improved （ P 〈 0.05 ） ; the time of loaded - swimming was significantly prolonged （P 〈 0.05 ）. It meant auricular acupressure pressing could be taken into consideration when there were therapeutic effects on mental fatigue of rats. Conclusion：Auricular acupressure pressing can improve the signs and symptoms of mental fatigue of rats.