摘要
Electrochemical oxidation of hydroquinone（1a） has been studied in the presence of 6-methyl-2-thiouracil（3a） and 6-propyl-2-thiouracil（3b） as nucleophiles in a DMF/buffer mixture,using cyclic voltammetry and controlled-potential coulometry.The results indicated that the p-quinone（2a） derived from 1a participates in a 1 4-Michael addition reaction with the thiouracil derivatives（3a–b） to form the corresponding hydroquinonethioether derivatives（6a–6b）.The electrosynthesis of these compounds（6a–b） has been successfully performed on carbon rod electrodes in an undivided cell in good yield and purity.
Electrochemical oxidation of hydroquinone（1a） has been studied in the presence of 6-methyl-2-thiouracil（3a） and 6-propyl-2-thiouracil（3b） as nucleophiles in a DMF/buffer mixture,using cyclic voltammetry and controlled-potential coulometry.The results indicated that the p-quinone（2a） derived from 1a participates in a 1 4-Michael addition reaction with the thiouracil derivatives（3a–b） to form the corresponding hydroquinonethioether derivatives（6a–6b）.The electrosynthesis of these compounds（6a–b） has been successfully performed on carbon rod electrodes in an undivided cell in good yield and purity.
基金
Semnan University Research Council for financial supports of this work
