超选择膀胱动脉化疗栓塞治疗中晚期膀胱癌

Superselective bladder artery infusion chemotherapy and embolization in treatment of middle and advanced stage of bladder cancer

目的 :采用经导管超选择性膀胱动脉化疗栓塞治疗中晚期膀胱癌并探讨其疗效、技术要点及并发症。方法 :15例经病理证实的中晚期膀胱癌 ,经两侧膀胱动脉局部灌注化疗 ,然后用碘油加 5 氟尿嘧啶及明胶海绵碎屑作栓塞治疗。结果 :CR +PR为 13例 (13 /15 ) ,NC为 2例 (2 /15 ) ,总有效率为 86.7% ,4例获Ⅱ期手术切除。结果 :采用经导管超选择膀胱动脉化疗栓塞是治疗中晚期膀胱癌的一种有效方法 ,部分患者还可获得Ⅱ期手术机会 。

Objective:Superselective urimary bladder arterial infusion chemotherapy and embolization was adopted for treatingmiddle and advanced stage of bladder cancer.The therapeutic effect,technique and complications were studied.Methods:15 cases of middle and advanced stage of bladder cancer were diagnosed by pathology.All 15 cases were treated by transarterial infusion,and then followed by lipiodol 5 Fu and gelfoam embolization.Results:CR+PR was 86.7%(13/15),NC was 13.3%(2/15).4 cases (4/15) were treated by surgery after arterial chemoembolization.Conclusion:Superselective urinary bladder arterial infusion chemotherapy and embolization is an effective therapy for the treatment of middle and advanced stage of bladder cancer.Some patients can be treated by surgery after the chemoembolization,the survival rate of bladder cancer could be further improved.