β射线治疗瘢痕疙瘩有效时机的探讨

Investigation of the best therapy time of keloids with β-ray treatment

目的 :探讨 β射线放射治疗瘢痕疙瘩的有效时机 ,以提高该法的疗效。 方法 :71例瘢痕疙瘩患者 ,用同一90 锶 90 钇放射性核素敷贴器 ,同样的剂量和方法治疗。根据治疗时机的不同分为三个治疗组。Ⅰ组、Ⅱ组分别于瘢痕疙瘩切除术后第 3～ 5天、拆线后 10～ 14天开始放疗 ;Ⅲ组未作瘢痕疙瘩切除术 ,直接放疗。随访时间 6个月至 2年。结果 :三个治疗组疗效对比有显著性差异 ,Ⅰ组疗效最佳 ,Ⅱ组次之 ,Ⅲ组最差。结论 :治疗瘢痕疙瘩时 ,在瘢痕切除术后加 β射线放疗 ,比单纯作放疗或切除术疗效好 ;术后 β射线放疗的时间宜尽早 ,术后第 3～ 5天尚未拆线即可进行 ,这样预防瘢痕疙瘩复发的疗效最好 。

Objective:To investigate the best therapy time of keloids with β ray treatment,in order to enchance its efficiency.Methods:71 keloids patients are treated with β ray in the same doses and methods.According the differences of their therapy times,they are divided into 3 groups.GroupⅠ is on the 3rd～5th day after keloids excision;GroupⅡ is in the 1th～2th week after removing stitch;GroupⅢ is directly treated with β ray without keloids excision.Results:The differences of therapy efficiency in 3 groups are very significant.GroupⅠis the best,GroupⅡ is better,GroupⅢ is the worst.Conclusion:The efficiency of keloids with β ray treating is better after excision than without excision,the best therapy time with β ray is on the 3th～5th day after excision without removing stitch.It can get the best efficiency to prevent keloids.