异体血输注对胃癌患者术后感染及伤口愈合影响的观察

The influence of allogeneic transfusion on postoperative infection and wound intention to the patients with gastric cancer

目的了解输血对恶性肿瘤患者术后感染及伤口愈合的影响。方法将 6 0例围术期胃癌分成 3组 (输血组 30例 ,输RBC组 12例及未输血组 18例 ) ,观察术后发热 ,感染发生率、白细胞、中性粒细胞及伤口愈合情况。结果术后最高体温 3组间差异无显著意义。发热持续时间 ,输血组最长 ,其次输RBC组 ,分别与未输血组比较差异有显著意义 (P <0 0 1) ,输血组与输RBC组比较差异无显著意义 (P >0 0 5 )。输血组合并感染 (37% )高于输RBC组 (33% )及未输血组 (11 1% ) ,输全血组与未输血组比较差异有显著意义 (P <0 0 5 )。其他两组比较差异无显著意义 (P >0 0 5 )。伤口愈合时间输血组最长 ,与未输血组比较差异有显著意义 (P <0 0 5 ) ;其他两组比较差异无显著意义 (P >0 0 5 )。输血组WBC 10 81± 3 93× 10 9/L、输RBC组 7 2± 3 80× 10 9/L、未输血组 7 34± 3 14× 10 9/L。输血组与未输血组比较差异有显著意义 (P <0 0 5 )。其他两组比较差异无显著意义 (P >0 0 5 )。N :输全血组 10 0 4× 10 9/L± 5 38;输RBC组 8 4× 10 9/L± 5 96 ;未输血组 5 42× 10 9/L± 2 74。输全血组最高 ,与未输血组比较差异有显著意义 (P <0 0 1) ,其他两组比较差异无显著意义 (P >0 0 5 )。结论输血增加恶性肿瘤术?

Objective To investigate the influence of blood transfusion on the postoperative wound intention and infection in the patients with gastric cancer. Method 60 patients with gastric cancer were divided into three groups: Group A including 30 cases accepted whole blood transfusion, Group B 12 cases accepted red blood cells transfusion, and other 18 cases without transfusion as control (Group C). The fever, local infection, white blood cells count, and wound intention were observed. Results After operation, there was no significant difference in the highest temperature among the three groups. The duration time of fever was shortest in Group C, there was significant difference between Group B and Group C ( P <0.01), significant difference between Group A and Group C ( P <0.01). The infections rate in Group A was the highest (37%), The healing time of surgical wound was the longest in Group A and Group C ( P <0.05). White blood cell count was the highest in Group A. Counclusion Blood transfusion can increase infectious rate and delay the surgical wound intention. Therefore, blood transfusion in patients with malignanacy should be limited. If it must be done, the transfusion of red blood cells prefers to that of whold blood.