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Claudin-1与卵巢癌相关性的研究进展 被引量：3

CLAUDIN-1 AND OVARIAN CANCER
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摘要 Claudin-1蛋白是一种闭合蛋白,也是细胞间紧密连接蛋白的主要组成部分,其特异性的组织表达,在保持紧密连接屏障功能和细胞极性方面具有重要作用。表达异常的Clandin-1蛋白与上皮性卵巢癌的转移和侵袭密切相关,本文综述了Claudin-1与卵巢癌相关性的研究进展。 Claudin-1 is a family of integral membrane tight junction（TJ） proteins. The tissuespecific expressions of claudin- 1 proteins perform specialized epithelial or endothelial functions including maintenance of ceil polarity and paracellular barrier functions. Many researches indicate that abnormal expression of claudin-1 has a relationship with the invasion and metastasis of ovarian cancer. This article reviewed the relationship of Claudin-1 and ovarian cancer.
作者 张承敏 斯琴 贾立周
机构地区 内蒙古医科大学附属人民医院
出处 《内蒙古医科大学学报》 2014年第2期193-196,共4页 Journal of Inner Mongolia Medical University
基金 内蒙古自治区自然科学基金项目(2012MS1088) 内蒙古医科大学肿瘤创新团队(2013)
关键词 CLAUDIN-1 卵巢癌 claudin- 1 ovarian cancer
分类号 R73-3 [医药卫生—肿瘤]
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参考文献32

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二级参考文献85

  • 1陈徐艰,郑树森.Claudin蛋白与恶性肿瘤关系的研究进展[J].国际外科学杂志,2006,33(5):380-383. 被引量：5
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共引文献38

同被引文献19

引证文献3

二级引证文献9

内蒙古医科大学学报
2014年 第2期

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