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人乳头瘤病毒检测在宫颈不典型鳞状上皮细胞患者中的应用

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摘要 目的探讨人乳头瘤病毒(HPV)检测在宫颈非典型鳞状上皮细胞(ASCUS)患者的临床意义及应用价值。方法本文对本院2010—2013年的收治的116例ASCUS的患者进行HPV检测,并且采用宫颈细胞学对感染类型进行诊断。结果①阴道镜活检结果中,宫颈鳞癌3例,宫颈湿疣及CINⅠ共36例,宫颈炎症65例,CINⅡ-Ⅲ12例。②HPV-DNA检测结果显示,54例患者呈现HPV阳性,高危型37例;HPV阴性62例。③阴道镜下宫颈活检的患者,HPV阳性组与HPV阴性组的炎症、宫颈湿疣、CINⅠ、CINⅡ-III比较具有统计学意义(P〈0.05)。④分型检测结果中,HPV低危型感染者与高危型HPV感染者宫颈湿疣、CINⅠ和宫颈癌检出率比较无统计学差异,但两者炎症和CINⅡ-Ⅲ病变检出率比较P〈0.05,有统计学差异。结论 HPV检测是ASCUS患者分流的有效方法,尤其是高危型HPV感染的ASCUS患者的诊断具有一定指导意义。
作者 刘莉萍
出处 《中国药物经济学》 2014年第5期181-182,192,共3页 China Journal of Pharmaceutical Economics
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