摘要
研究了1 ，1 ，1-三氨基甲基丙烷（Tamp）锌（Ⅱ）配合物作水解酶模拟物催化对硝基苯酚醋酸酯（NA）水解的动力学。结果表明：催化水解速率对底物（NA）及配合物（Zntamp）浓度均呈一级反应，水解速率遵循速率方程ｄC／dt＝（koba［Zntamp］＋koh［OH-］＋…）［NA］；在中性和弱碱性…条件下能很好地催化NA酯的水解，PH＝9．000时，表观催化速率常数koba＝0．7185mol-1·L·s-1，优于国际上同类研究报道的结果；催化作用受酸碱平衡的控制，结合PH滴定结果，提出了催化反应机理。
The hydrolytic kinetics of p-nitrophenol acetate(NA) catalyzed by zinc (Ⅱ) complex of 1, l,1- tris(aminomethyl) propane(Tamp) has been studied. It was shown that the catalytic rate follows the law of first-order reaction for both zinc (Ⅱ) complex and NA concentrations respectively; the hydrolytic rate equation is dC/d t = (k.obs.[Zntamp] + KOH [OH - ] +…) [NA]; this complex can catalyze NA hydrolysis effectively under a neutral or slightly basic condition; the k.b, value equals 0. 7185mol-l' L. s- 1 when PH 9. 000, which is better than the similar results of international investigation reported up to now; the catalysis is controlled by the equilibrium of acid and base. Combined with the results of PH drop scale method, a mechanism of catalyzed reaction is put forward.
出处
《无机化学学报》
SCIE
CAS
CSCD
北大核心
2001年第2期234-238,共5页
Chinese Journal of Inorganic Chemistry
