超声弹性成像和常规超声检查对甲状腺结节诊断价值的对比分析

Contrastive analysis of ultrasound elastography and conventional ultrasound examination in the diagnosis of thyroid nodules

目的:探讨超声弹性成像对甲状腺结节的诊断价值。方法:85例患者104个甲状腺结节采用常规超声和超声弹性成像检查,比较两种检查方式的灵敏度、特异度、阳性预测值、阴性预测值和诊断准确率。结果:104个甲状腺结节经手术后病理证实良性结节78个,恶性结节26个。常规超声对良恶性结节诊断的灵敏度为61.5%,特异度为69.2%,阳性预测值为40.0%,阴性预测值为84.4%,诊断准确率为67.3%;超声弹性成像对良恶性结节诊断的灵敏度为92.3%,特异度为91.0%,阳性预测值为77.4%,阴性预测值为97.3%,诊断准确率为91.4%。各项统计指标比较,超声弹性成像优于常规超声检查(P<0.05)。结论:超声弹性成像通过硬度分级对甲状腺结节进行定性诊断,大大提高了诊断准确率,在甲状腺结节性疾病的诊断中具有重要的临床价值。

Objective： To explore the value of ultrasonic elastography in diagnosis of thyroid nodules. Methods： 85 patients（ including 104 thyroid nodules） were examined by conventional ultrasound and ultrasound elastography, the sensitivity,specificity,positive predictive value,and the negative predictive value and diagnostic accuracy of two methods were compared. Results： 78 benign nodules and 26 malignant nodules were confirmed by pathology after operation in 104 thyroid nodules,the sensitivity of ultrasonography in diagnosis of benign and malignant nodules was 61. 5%,the specificity,the positive predictive value,the negative predictive value,the diagnostic accuracy were 69. 2%,40%,84. 4% and 67. 3%; the sensitivity of ultrasound elastography in the diagnosis of benign and malignant nodules was 92. 3%,the specificity,the positive predictive value,the negative predictive value and the diagnostic accuracy were 91%,77. 4%,97. 3% and 91. 4%; the statistical indicators were compared,ultrasound elastography was superior to the conventional ultrasonography,the difference had a statistical significance. Conclusion： Ultrasound elastography,a new imaging technique,can diagnose thyroid nodules qualitatively according to hardness grades,and improves the accuracy of diagnosis. It has important clinical value in the diagnosis of thyroid nodular disease.