空腹血糖受损的中老年人血糖变化及转归的影响因素分析

Study on the change and outcome of fasting plasma glucose in elderly people with impaired fasting glucose

[目的]了解空腹血糖受损（ IFG）的中老年人空腹血糖变化及转归情况，并分析其影响因素。[方法]采用多阶段随机抽样方法，在上海市闸北区随机抽取2个街道，再按随机抽样方法确定居委会和楼组。选择年龄≥40岁、空腹血糖（FPG）6．1～6．9 mmol/L的常住人口进入本次研究，共203人。对该部分人群于2011-2012年间2次清晨空腹采静脉血样，检测FPG、总胆固醇（ TC）、三酰甘油（ TG）、高密度脂蛋白（ HDL-C）、低密度脂蛋白（ LDL）等生化指标，测量身高、体重、腰围、臀围，并于2012年通过问卷调查了解其生活方式及对糖尿病的认知水平。[结果]对IFG人群连续观测2年，FPG总体水平有所上升，差异有统计学意义。 FPG1、FPG2分别有37．44％、30．05％的居民升高到7．0 mmol/L以上，同时有38．42％、33．50％的居民FPG下降到6．1 mmol/L以下。被确诊为糖尿病者占9．85％。多因素分析发现BMI为IFG人群FPG升高的危险因素。[结论]40岁以上IFG人群FPG水平2年内随时间总体有所升高。 BMI是IFG人群FPG水平的影响因素。

To study the changes and outcome of fasting plasma glucose and its influ-encing factors in elderly people with impaired fasting glucose （ IFG） . [ Methods] The subjects were a-bove 40 years old and their FPG values were between 6.1 -6.9 mmol/L.The FPG,TC,TG,HDL-C, LDL,height,weight,waist circumference ,hip circumference of the subjects were measured 2 times.A ques-tionnaire about life style and cognition about diabetes was conducted in 2012 among the subjects . [ Results] The IFG subjects were under continuous observation for 2 years.Their overall level of IFG was increased , which was found to be statistically significant .Those diagnosed with diabetes accounted for 9 .85%of the total .Logistic Regression Analysis showed that BMI was the risk factor for IFG subjects in the rise of FPG. [Conclusion] On the whole, for IFG people of 40 or above, overall FGP value was on a growth trend during the past 2 years.The influencing factor is thought to be BMI .