4WHO Consultation Group.Definition,diagnosis and classification of diabetes mellitus and its complications.2nd.Part 1:Diagnosis and classification of diabetes mellitus WHO/NCD/NCS/99.Genena:World Health Organisation,1999:1-59.
5中华人民共和国卫生部.新药临床研究指导原则.第1辑.1993:82-85.
6Bruce DG, Chisholm DJ, Leonare H, et al . In early prandial insulin secretion in non-insulin-dependent diabetes[J] . Diabetes, 1988,37: 736-743.
7UK Prospective Diabetes Study (UKPDS) group . Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complication in patients with type 2 diabetes(UKPDS 33 ) [J ]. Lancet, 1998,352:837-853.
8American Diabetes Association. Implications of the Diabetes Control and Complications Trial[J]. Diabetes Care,2000,23 (Suppl Ⅰ): S24- S26.
9Purrello F, Rabuazza AM. Metabolic factors that affect betacell function and survival. Diabet Nutr Metab, 2000, 13: 84-91.
10Sivitz WI. Lipotoxieity and glueotoxieity in type 2 diabetes. Effects on development and progression. Postgrad Med, 2001,109: 55-59,63-64.
